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Page 1
Targetable leukaemia dependency on noncanonical PI3Kγ signalling.
Luo Q, Raulston EG, Prado MA, Wu X, Gritsman K, Whalen KS, Yan K, Booth CAG, Xu R, van Galen P, Doench JG, Shimony S, Long HW, Neuberg DS, Paulo JA, Lane AA. Luo Q, et al. Among authors: long hw. Nature. 2024 May 8. doi: 10.1038/s41586-024-07410-3. Online ahead of print. Nature. 2024. PMID: 38720074
Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
Goyette MA, Stevens LE, DePinho CR, Seehawer M, Nishida J, Li Z, Wilde CM, Li R, Qiu X, Pyke AL, Zhao S, Lim K, Tender GS, Northey JJ, Riley NM, Long HW, Bertozzi CR, Weaver VM, Polyak K. Goyette MA, et al. Among authors: long hw. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2322688121. doi: 10.1073/pnas.2322688121. Epub 2024 May 6. Proc Natl Acad Sci U S A. 2024. PMID: 38709925 Free article.
Thio-2 inhibits key signaling pathways required for the development and progression of castration resistant prostate cancer.
Neeb A, Figueiredo I, Bogdan D, Cato L, Stober J, Jiménez-Vacas JM, Gourain V, Lee II, Seeger R, Muhle-Goll C, Gurel B, Welti J, Nava Rodrigues D, Rekowski J, Qiu X, Jiang Y, Di Micco P, Mateos B, Bielskutė S, Riisnaes R, Ferreira A, Miranda S, Crespo M, Buroni L, Ning J, Carreira S, Bräse S, Jung N, Gräßle S, Swain A, Salvatella X, Plymate SR, Al-Lazikani B, Long HW, Yuan W, Brown M, Cato ACB, de Bono JS, Sharp A. Neeb A, et al. Among authors: long hw. Mol Cancer Ther. 2024 Feb 27. doi: 10.1158/1535-7163.MCT-23-0354. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38412481
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer.
Duplaquet L, So K, Ying AW, Li X, Li Y, Qiu X, Li R, Singh S, Wu XS, Liu Q, Qi J, Somerville TDD, Heiling H, Mazzola E, Lee Y, Zoller T, Vakoc CR, Doench JG, Forrester WC, Abrams T, Long HW, Niederst MJ, Kadoch C, Oser MG. Duplaquet L, et al. Among authors: long hw. bioRxiv [Preprint]. 2024 Jan 24:2024.01.21.576304. doi: 10.1101/2024.01.21.576304. bioRxiv. 2024. PMID: 38328215 Free PMC article. Preprint.
Targetable leukemia dependency on noncanonical PI3Kγ signaling.
Luo Q, Raulston EG, Prado MA, Wu X, Gritsman K, Yan K, Booth CAG, Xu R, van Galen P, Doench JG, Shimony S, Long HW, Neuberg DS, Paulo JA, Lane AA. Luo Q, et al. Among authors: long hw. bioRxiv [Preprint]. 2023 Dec 15:2023.12.15.571909. doi: 10.1101/2023.12.15.571909. bioRxiv. 2023. PMID: 38328043 Free PMC article. Preprint.
Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer.
Poluben L, Nouri M, Liang J, Varkaris A, Ersoy-Fazlioglu B, Voznesensky O, Lee II, Qiu X, Cato L, Seo JH, Freedman ML, Sowalsky AG, Lack NA, Corey E, Nelson PS, Brown M, Long HW, Balk SP, Russo JW. Poluben L, et al. Among authors: long hw. bioRxiv [Preprint]. 2024 Jan 12:2024.01.10.575110. doi: 10.1101/2024.01.10.575110. bioRxiv. 2024. PMID: 38260576 Free PMC article. Preprint.
Heterogeneity and transcriptional drivers of triple-negative breast cancer.
Jovanović B, Temko D, Stevens LE, Seehawer M, Fassl A, Murphy K, Anand J, Garza K, Gulvady A, Qiu X, Harper NW, Daniels VW, Xiao-Yun H, Ge JY, Alečković M, Pyrdol J, Hinohara K, Egri SB, Papanastasiou M, Vadhi R, Font-Tello A, Witwicki R, Peluffo G, Trinh A, Shu S, Diciaccio B, Ekram MB, Subedee A, Herbert ZT, Wucherpfennig KW, Letai AG, Jaffe JD, Sicinski P, Brown M, Dillon D, Long HW, Michor F, Polyak K. Jovanović B, et al. Among authors: long hw. Cell Rep. 2023 Dec 26;42(12):113564. doi: 10.1016/j.celrep.2023.113564. Epub 2023 Dec 14. Cell Rep. 2023. PMID: 38100350 Free PMC article.
Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer.
Alečković M, Li Z, Zhou N, Qiu X, Lulseged B, Foidart P, Huang XY, Garza K, Shu S, Kesten N, Li R, Lim K, Garrido-Castro AC, Guerriero JL, Qi J, Long HW, Polyak K. Alečković M, et al. Among authors: long hw. Mol Cancer Ther. 2023 Nov 1;22(11):1304-1318. doi: 10.1158/1535-7163.MCT-23-0303. Mol Cancer Ther. 2023. PMID: 37676980 Free PMC article.
108 results