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A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates.
Douglas AD, Baldeviano GC, Jin J, Miura K, Diouf A, Zenonos ZA, Ventocilla JA, Silk SE, Marshall JM, Alanine DGW, Wang C, Edwards NJ, Leiva KP, Gomez-Puerta LA, Lucas CM, Wright GJ, Long CA, Royal JM, Draper SJ. Douglas AD, et al. Among authors: long ca. Nat Commun. 2019 Apr 26;10(1):1953. doi: 10.1038/s41467-019-09894-4. Nat Commun. 2019. PMID: 31028254 Free PMC article.
A recombinant vaccine expressed in the milk of transgenic mice protects Aotus monkeys from a lethal challenge with Plasmodium falciparum.
Stowers AW, Chen Lh LH, Zhang Y, Kennedy MC, Zou L, Lambert L, Rice TJ, Kaslow DC, Saul A, Long CA, Meade H, Miller LH. Stowers AW, et al. Among authors: long ca. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):339-44. doi: 10.1073/pnas.012590199. Epub 2001 Dec 18. Proc Natl Acad Sci U S A. 2002. PMID: 11752405 Free PMC article.
Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria.
Malkin EM, Diemert DJ, McArthur JH, Perreault JR, Miles AP, Giersing BK, Mullen GE, Orcutt A, Muratova O, Awkal M, Zhou H, Wang J, Stowers A, Long CA, Mahanty S, Miller LH, Saul A, Durbin AP. Malkin EM, et al. Among authors: long ca. Infect Immun. 2005 Jun;73(6):3677-85. doi: 10.1128/IAI.73.6.3677-3685.2005. Infect Immun. 2005. PMID: 15908397 Free PMC article. Clinical Trial.
Immunity to recombinant plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity.
Singh S, Miura K, Zhou H, Muratova O, Keegan B, Miles A, Martin LB, Saul AJ, Miller LH, Long CA. Singh S, et al. Among authors: long ca. Infect Immun. 2006 Aug;74(8):4573-80. doi: 10.1128/IAI.01679-05. Infect Immun. 2006. PMID: 16861644 Free PMC article.
357 results