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Page 1
The genomics of heart failure: design and rationale of the HERMES consortium.
Lumbers RT, Shah S, Lin H, Czuba T, Henry A, Swerdlow DI, Mälarstig A, Andersson C, Verweij N, Holmes MV, Ärnlöv J, Svensson P, Hemingway H, Sallah N, Almgren P, Aragam KG, Asselin G, Backman JD, Biggs ML, Bloom HL, Boersma E, Brandimarto J, Brown MR, Brunner-La Rocca HP, Carey DJ, Chaffin MD, Chasman DI, Chazara O, Chen X, Chen X, Chung JH, Chutkow W, Cleland JGF, Cook JP, de Denus S, Dehghan A, Delgado GE, Denaxas S, Doney AS, Dörr M, Dudley SC, Engström G, Esko T, Fatemifar G, Felix SB, Finan C, Ford I, Fougerousse F, Fouodjio R, Ghanbari M, Ghasemi S, Giedraitis V, Giulianini F, Gottdiener JS, Gross S, Guðbjartsson DF, Gui H, Gutmann R, Haggerty CM, van der Harst P, Hedman ÅK, Helgadottir A, Hillege H, Hyde CL, Jacob J, Jukema JW, Kamanu F, Kardys I, Kavousi M, Khaw KT, Kleber ME, Køber L, Koekemoer A, Kraus B, Kuchenbaecker K, Langenberg C, Lind L, Lindgren CM, London B, Lotta LA, Lovering RC, Luan J, Magnusson P, Mahajan A, Mann D, Margulies KB, Marston NA, März W, McMurray JJV, Melander O, Melloni G, Mordi IR, Morley MP, Morris AD, Morris AP, Morrison AC, Nagle MW, Nelson CP, Newton-Cheh C, Niessner A, Niiranen T, Nowak C, O'Donoghue ML, Owens AT, Palmer CNA, Paré G,… See abstract for full author list ➔ Lumbers RT, et al. Among authors: london b. ESC Heart Fail. 2021 Dec;8(6):5531-5541. doi: 10.1002/ehf2.13517. Epub 2021 Sep 3. ESC Heart Fail. 2021. PMID: 34480422 Free PMC article.
A sodium channel pore mutation causing Brugada syndrome.
Pfahnl AE, Viswanathan PC, Weiss R, Shang LL, Sanyal S, Shusterman V, Kornblit C, London B, Dudley SC Jr. Pfahnl AE, et al. Among authors: london b. Heart Rhythm. 2007 Jan;4(1):46-53. doi: 10.1016/j.hrthm.2006.09.031. Epub 2006 Sep 28. Heart Rhythm. 2007. PMID: 17198989 Free PMC article.
Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias.
London B, Michalec M, Mehdi H, Zhu X, Kerchner L, Sanyal S, Viswanathan PC, Pfahnl AE, Shang LL, Madhusudanan M, Baty CJ, Lagana S, Aleong R, Gutmann R, Ackerman MJ, McNamara DM, Weiss R, Dudley SC Jr. London B, et al. Circulation. 2007 Nov 13;116(20):2260-8. doi: 10.1161/CIRCULATIONAHA.107.703330. Epub 2007 Oct 29. Circulation. 2007. PMID: 17967977 Free PMC article.
Targeting device therapy: genomics of sudden death.
Frangiskakis JM, London B. Frangiskakis JM, et al. Among authors: london b. Heart Fail Clin. 2010 Jan;6(1):93-100. doi: 10.1016/j.hfc.2009.08.005. Heart Fail Clin. 2010. PMID: 19945065 Free PMC article. Review.
Statins Decrease Oxidative Stress and ICD Therapies.
Bloom HL, Shukrullah I, Veledar E, Gutmann R, London B, Dudley SC. Bloom HL, et al. Among authors: london b. Cardiol Res Pract. 2010;2010:253803. doi: 10.4061/2010/253803. Epub 2010 Mar 25. Cardiol Res Pract. 2010. PMID: 20369058 Free PMC article.
Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy.
Refaat MM, Lubitz SA, Makino S, Islam Z, Frangiskakis JM, Mehdi H, Gutmann R, Zhang ML, Bloom HL, MacRae CA, Dudley SC, Shalaby AA, Weiss R, McNamara DM, London B, Ellinor PT. Refaat MM, et al. Among authors: london b. Heart Rhythm. 2012 Mar;9(3):390-6. doi: 10.1016/j.hrthm.2011.10.016. Epub 2011 Oct 17. Heart Rhythm. 2012. PMID: 22004663 Free PMC article.
Angiotensin receptor type 1 single nucleotide polymorphism 1166A/C is associated with malignant arrhythmias and altered circulating miR-155 levels in patients with chronic heart failure.
Blanco RR, Austin H, Vest RN 3rd, Valadri R, Li W, Lassegue B, Song Q, London B, Dudley SC, Bloom HL, Searles CD, Zafari AM. Blanco RR, et al. Among authors: london b. J Card Fail. 2012 Sep;18(9):717-23. doi: 10.1016/j.cardfail.2012.06.531. Epub 2012 Aug 9. J Card Fail. 2012. PMID: 22939041 Free PMC article.
Effect of angiotensin-converting enzyme inhibitors and receptor blockers on appropriate implantable cardiac defibrillator shock in patients with severe systolic heart failure (from the GRADE Multicenter Study).
AlJaroudi WA, Refaat MM, Habib RH, Al-Shaar L, Singh M, Gutmann R, Bloom HL, Dudley SC, Ellinor PT, Saba SF, Shalaby AA, Weiss R, McNamara DM, Halder I, London B; Genetic Risk Assessment of Defibrillator Events Investigators. AlJaroudi WA, et al. Among authors: london b. Am J Cardiol. 2015 Apr 1;115(7):924-31. doi: 10.1016/j.amjcard.2015.01.020. Epub 2015 Jan 15. Am J Cardiol. 2015. PMID: 25682436 Free PMC article. Clinical Trial.
220 results