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Page 1
Biomimetic synthesis of Tramadol.
Lecerf-Schmidt F, Haudecoeur R, Peres B, Ferreira Queiroz MM, Marcourt L, Challal S, Ferreira Queiroz E, Sotoing Taiwe G, Lomberget T, Le Borgne M, Wolfender JL, De Waard M, Robins RJ, Boumendjel A. Lecerf-Schmidt F, et al. Among authors: lomberget t. Chem Commun (Camb). 2015 Oct 4;51(77):14451-3. doi: 10.1039/c5cc05948h. Epub 2015 Aug 12. Chem Commun (Camb). 2015. PMID: 26267411
Occurrence of the synthetic analgesic tramadol in an African medicinal plant.
Boumendjel A, Sotoing Taïwe G, Ngo Bum E, Chabrol T, Beney C, Sinniger V, Haudecoeur R, Marcourt L, Challal S, Ferreira Queiroz E, Souard F, Le Borgne M, Lomberget T, Depaulis A, Lavaud C, Robins R, Wolfender JL, Bonaz B, De Waard M. Boumendjel A, et al. Among authors: lomberget t. Angew Chem Int Ed Engl. 2013 Nov 4;52(45):11780-4. doi: 10.1002/anie.201305697. Epub 2013 Sep 6. Angew Chem Int Ed Engl. 2013. PMID: 24014188 No abstract available.
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site.
Bestgen B, Krimm I, Kufareva I, Kamal AAM, Seetoh WG, Abell C, Hartmann RW, Abagyan R, Cochet C, Le Borgne M, Engel M, Lomberget T. Bestgen B, et al. Among authors: lomberget t. J Med Chem. 2019 Feb 28;62(4):1803-1816. doi: 10.1021/acs.jmedchem.8b01766. Epub 2019 Feb 18. J Med Chem. 2019. PMID: 30689953 Free PMC article.
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action.
Bestgen B, Kufareva I, Seetoh W, Abell C, Hartmann RW, Abagyan R, Le Borgne M, Filhol O, Cochet C, Lomberget T, Engel M. Bestgen B, et al. Among authors: lomberget t. J Med Chem. 2019 Feb 28;62(4):1817-1836. doi: 10.1021/acs.jmedchem.8b01765. Epub 2019 Feb 13. J Med Chem. 2019. PMID: 30689946 Free PMC article.
Fragment Linking Strategies for Structure-Based Drug Design.
Bancet A, Raingeval C, Lomberget T, Le Borgne M, Guichou JF, Krimm I. Bancet A, et al. Among authors: lomberget t. J Med Chem. 2020 Oct 22;63(20):11420-11435. doi: 10.1021/acs.jmedchem.0c00242. Epub 2020 Jun 23. J Med Chem. 2020. PMID: 32539387 Review.
Synthesis of new steroidal inhibitors of P-glycoprotein-mediated multidrug resistance and biological evaluation on K562/R7 erythroleukemia cells.
de Ravel MR, Alameh G, Melikian M, Mahiout Z, Emptoz-Bonneton A, Matera EL, Lomberget T, Barret R, Rocheblave L, Walchshofer N, Beltran S, El Jawad L, Mappus E, Grenot C, Pugeat M, Dumontet C, Le Borgne M, Cuilleron CY. de Ravel MR, et al. Among authors: lomberget t. J Med Chem. 2015 Feb 26;58(4):1832-45. doi: 10.1021/jm501676v. Epub 2015 Feb 11. J Med Chem. 2015. PMID: 25634041
In vitro modulation of multidrug resistance by pregnane steroids and in vivo inhibition of tumour development by 7α-OBz-11α(R)-OTHP-5β-pregnanedione in K562/R7 and H295R cell xenografts.
Alameh G, Emptoz-Bonneton A, Rolland de Ravel M, Matera EL, Mappus E, Balaguer P, Rocheblave L, Lomberget T, Dumontet C, Le Borgne M, Pugeat M, Grenot C, Cuilleron CY. Alameh G, et al. Among authors: lomberget t. J Enzyme Inhib Med Chem. 2019 Dec;34(1):684-691. doi: 10.1080/14756366.2019.1575825. J Enzyme Inhib Med Chem. 2019. PMID: 30777494 Free PMC article.
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors.
Kufareva I, Bestgen B, Brear P, Prudent R, Laudet B, Moucadel V, Ettaoussi M, Sautel CF, Krimm I, Engel M, Filhol O, Borgne ML, Lomberget T, Cochet C, Abagyan R. Kufareva I, et al. Among authors: lomberget t. Sci Rep. 2019 Nov 4;9(1):15893. doi: 10.1038/s41598-019-52141-5. Sci Rep. 2019. PMID: 31685885 Free PMC article.
24 results