Loenarz C - Search Results

1

Non-canonical nucleosides: Biomimetic triphosphorylation, incorporation into mRNA and effects on translation and structure.

Benčić P, Keppler M, Kuge M, Qiu D, Schütte LM, Häner M, Strack K, Jessen HJ, Andexer JN, Loenarz C. Benčić P, et al. Among authors: loenarz c. FEBS J. 2023 Oct;290(20):4899-4920. doi: 10.1111/febs.16889. Epub 2023 Jun 26. FEBS J. 2023. PMID: 37329249

2

A Cobalamin-Dependent Radical SAM Enzyme Catalyzes the Unique C_α -Methylation of Glutamine in Methyl-Coenzyme M Reductase.

Gagsteiger J, Jahn S, Heidinger L, Gericke L, Andexer JN, Friedrich T, Loenarz C, Layer G. Gagsteiger J, et al. Among authors: loenarz c. Angew Chem Int Ed Engl. 2022 Aug 8;61(32):e202204198. doi: 10.1002/anie.202204198. Epub 2022 Jun 29. Angew Chem Int Ed Engl. 2022. PMID: 35638156 Free PMC article.

3

β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner.

Eisenbeis VB, Qiu D, Gorka O, Strotmann L, Liu G, Prucker I, Su XB, Wilson MSC, Ritter K, Loenarz C, Groß O, Saiardi A, Jessen HJ. Eisenbeis VB, et al. Among authors: loenarz c. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2306868120. doi: 10.1073/pnas.2306868120. Epub 2023 Aug 14. Proc Natl Acad Sci U S A. 2023. PMID: 37579180 Free PMC article.

4

YcfD_RM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase.

Sekirnik R, Wilkins SE, Bush J, Tarhonskaya H, Münzel M, Hussein A, Flashman E, Mohammed S, McDonough MA, Loenarz C, Schofield CJ. Sekirnik R, et al. Among authors: loenarz c. Extremophiles. 2018 May;22(3):553-562. doi: 10.1007/s00792-018-1016-9. Epub 2018 Mar 9. Extremophiles. 2018. PMID: 29523972 Free PMC article.

5

Studies on the Substrate Selectivity of the Hypoxia-Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain.

Abboud MI, Chowdhury R, Leung IKH, Lippl K, Loenarz C, Claridge TDW, Schofield CJ. Abboud MI, et al. Among authors: loenarz c. Chembiochem. 2018 Nov 2;19(21):2262-2267. doi: 10.1002/cbic.201800246. Epub 2018 Sep 26. Chembiochem. 2018. PMID: 30144273

6

An Oxygen Sensation: Progress in Macromolecule Hydroxylation Triggered by the Elucidation of Cellular Oxygen Sensing.

Loenarz C. Loenarz C. Angew Chem Int Ed Engl. 2020 Mar 2;59(10):3776-3780. doi: 10.1002/anie.201913263. Epub 2020 Jan 21. Angew Chem Int Ed Engl. 2020. PMID: 31961479 Review.

7

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding.

Thinnes CC, Lohans CT, Abboud MI, Yeh TL, Tumber A, Nowak RP, Attwood M, Cockman ME, Oppermann U, Loenarz C, Schofield CJ. Thinnes CC, et al. Among authors: loenarz c. Chemistry. 2019 Feb 6;25(8):2019-2024. doi: 10.1002/chem.201804790. Epub 2019 Jan 8. Chemistry. 2019. PMID: 30427558 Free PMC article.

8

Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase.

Yue WW, Hozjan V, Ge W, Loenarz C, Cooper CD, Schofield CJ, Kavanagh KL, Oppermann U, McDonough MA. Yue WW, et al. Among authors: loenarz c. FEBS Lett. 2010 Feb 19;584(4):825-30. doi: 10.1016/j.febslet.2009.12.055. Epub 2010 Jan 12. FEBS Lett. 2010. PMID: 20067792 Free article.

9

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.

Ge W, Wolf A, Feng T, Ho CH, Sekirnik R, Zayer A, Granatino N, Cockman ME, Loenarz C, Loik ND, Hardy AP, Claridge TDW, Hamed RB, Chowdhury R, Gong L, Robinson CV, Trudgian DC, Jiang M, Mackeen MM, Mccullagh JS, Gordiyenko Y, Thalhammer A, Yamamoto A, Yang M, Liu-Yi P, Zhang Z, Schmidt-Zachmann M, Kessler BM, Ratcliffe PJ, Preston GM, Coleman ML, Schofield CJ. Ge W, et al. Among authors: loenarz c. Nat Chem Biol. 2012 Dec;8(12):960-962. doi: 10.1038/nchembio.1093. Epub 2012 Oct 28. Nat Chem Biol. 2012. PMID: 23103944 Free PMC article.

10

Biomimetic S-Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes.

Gericke L, Mhaindarkar D, Karst LC, Jahn S, Kuge M, Mohr MKF, Gagsteiger J, Cornelissen NV, Wen X, Mordhorst S, Jessen HJ, Rentmeister A, Seebeck FP, Layer G, Loenarz C, Andexer JN. Gericke L, et al. Among authors: loenarz c. Chembiochem. 2023 May 2;24(9):e202300133. doi: 10.1002/cbic.202300133. Epub 2023 Apr 4. Chembiochem. 2023. PMID: 36942622

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