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Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis.
Chaudagar K, Hieromnimon HM, Kelley A, Labadie B, Shafran J, Rameshbabu S, Drovetsky C, Bynoe K, Solanki A, Markiewicz E, Fan X, Loda M, Patnaik A. Chaudagar K, et al. Among authors: loda m. bioRxiv [Preprint]. 2023 May 23:2023.05.23.540590. doi: 10.1101/2023.05.23.540590. bioRxiv. 2023. PMID: 37292972 Free PMC article. Updated. Preprint.
Distinct mesenchymal cell states mediate prostate cancer progression.
Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Jere M, Unkenholz C, Alexanderani MK, Khani F, de Almeida FN, Abate-Shen C, Greenblatt MB, Rickman DS, Barbieri CE, Robinson BD, Marchionni L, Loda M. Pakula H, et al. Among authors: loda m. bioRxiv [Preprint]. 2023 Apr 1:2023.03.29.534769. doi: 10.1101/2023.03.29.534769. bioRxiv. 2023. PMID: 37034687 Free PMC article. Updated. Preprint.
NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer.
Li JJ, Vasciaveo A, Karagiannis D, Sun Z, Chen X, Socciarelli F, Frankenstein Z, Zou M, Pannellini T, Chen Y, Gardner K, Robinson BD, de Bono J, Abate-Shen C, Rubin MA, Loda M, Sawyers CL, Califano A, Lu C, Shen MM. Li JJ, et al. Among authors: loda m. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549585. doi: 10.1101/2023.07.18.549585. bioRxiv. 2023. PMID: 37502956 Free PMC article. Preprint.
Canonical AREs are tumor suppressive regulatory elements in the prostate.
Augello MA, Chen X, Liu D, Lin K, Hakansson A, Sjöström M, Khani F, Deonarine LD, Liu Y, Travascio-Green J, Wu J, Loda M, Feng FY, Robinson BD, Davicioni E, Sboner A, Barbieri CE. Augello MA, et al. Among authors: loda m. bioRxiv [Preprint]. 2024 Feb 27:2024.02.23.581466. doi: 10.1101/2024.02.23.581466. bioRxiv. 2024. PMID: 38464162 Free PMC article. Preprint.
Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps.
Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J, Shaiber A, Afshinnekoo E, MacKay M, Bram Y, Chandar V, Geiger H, Craney A, Velu P, Melnick AM, Hajirasouliha I, Beheshti A, Taylor D, Saravia-Butler A, Singh U, Wurtele ES, Schisler J, Fennessey S, Corvelo A, Zody MC, Germer S, Salvatore S, Levy S, Wu S, Tatonetti N, Shapira S, Salvatore M, Loda M, Westblade LF, Cushing M, Rennert H, Kriegel AJ, Elemento O, Imielinski M, Borczuk AC, Meydan C, Schwartz RE, Mason CE. Park J, et al. Among authors: loda m. bioRxiv [Preprint]. 2021 Mar 9:2021.03.08.434433. doi: 10.1101/2021.03.08.434433. bioRxiv. 2021. PMID: 33758858 Free PMC article. Preprint.
Federated benchmarking of medical artificial intelligence with MedPerf.
Karargyris A, Umeton R, Sheller MJ, Aristizabal A, George J, Wuest A, Pati S, Kassem H, Zenk M, Baid U, Narayana Moorthy P, Chowdhury A, Guo J, Nalawade S, Rosenthal J, Kanter D, Xenochristou M, Beutel DJ, Chung V, Bergquist T, Eddy J, Abid A, Tunstall L, Sanseviero O, Dimitriadis D, Qian Y, Xu X, Liu Y, Goh RSM, Bala S, Bittorf V, Reddy Puchala S, Ricciuti B, Samineni S, Sengupta E, Chaudhari A, Coleman C, Desinghu B, Diamos G, Dutta D, Feddema D, Fursin G, Huang X, Kashyap S, Lane N, Mallick I; FeTS Consortium; BraTS-2020 Consortium; AI4SafeChole Consortium; Mascagni P, Mehta V, Ferro Moraes C, Natarajan V, Nikolov N, Padoy N, Pekhimenko G, Reddi VJ, Reina GA, Ribalta P, Singh A, Thiagarajan JJ, Albrecht J, Wolf T, Miller G, Fu H, Shah P, Xu D, Yadav P, Talby D, Awad MM, Howard JP, Rosenthal M, Marchionni L, Loda M, Johnson JM, Bakas S, Mattson P. Karargyris A, et al. Among authors: loda m. Nat Mach Intell. 2023 Jul;5(7):799-810. doi: 10.1038/s42256-023-00652-2. Epub 2023 Jul 17. Nat Mach Intell. 2023. PMID: 38706981 Free PMC article.
Author Correction: An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB.
Min J, Zaslavsky A, Fedele G, McLaughlin SK, Reczek EE, De Raedt T, Guney I, Strochlic DE, MacConaill LE, Beroukhim R, Bronson RT, Ryeom S, Hahn WC, Loda M, Cichowski K. Min J, et al. Among authors: loda m. Nat Med. 2024 Feb 21. doi: 10.1038/s41591-024-02866-2. Online ahead of print. Nat Med. 2024. PMID: 38383797 No abstract available.
Distinct mesenchymal cell states mediate prostate cancer progression.
Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Socciarelli F, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Dinalankara W, Jere M, Valencia I, Saladino C, Stone J, Unkenholz C, Garner R, Alexanderani MK, Khani F, de Almeida FN, Abate-Shen C, Greenblatt MB, Rickman DS, Barbieri CE, Robinson BD, Marchionni L, Loda M. Pakula H, et al. Among authors: loda m. Nat Commun. 2024 Jan 8;15(1):363. doi: 10.1038/s41467-023-44210-1. Nat Commun. 2024. PMID: 38191471 Free PMC article.
494 results