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Viral vectors for malaria vaccine development.
Li S, Locke E, Bruder J, Clarke D, Doolan DL, Havenga MJ, Hill AV, Liljestrom P, Monath TP, Naim HY, Ockenhouse C, Tang DC, Van Kampen KR, Viret JF, Zavala F, Dubovsky F. Li S, et al. Among authors: locke e. Vaccine. 2007 Mar 30;25(14):2567-74. doi: 10.1016/j.vaccine.2006.07.035. Epub 2006 Aug 1. Vaccine. 2007. PMID: 16914237 Free PMC article. Review.
Towards validated assays for key immunological outcomes in malaria vaccine development.
OPTIMALVAC consortium; Cavanagh DR, Dubois PM, Holtel A, Kisser A, Leroy O, Locke E, Moorthy VS, Remarque EJ, Shi YP. OPTIMALVAC consortium, et al. Among authors: locke e. Vaccine. 2011 Apr 12;29(17):3093-5. doi: 10.1016/j.vaccine.2011.01.070. Epub 2011 Feb 4. Vaccine. 2011. PMID: 21296116 Free article. No abstract available.
A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Beutler N, Pholcharee T, Oyen D, Flores-Garcia Y, MacGill RS, Garcia E, Calla J, Parren M, Yang L, Volkmuth W, Locke E, Regules JA, Dutta S, Emerling D, Early AM, Neafsey DE, Winzeler EA, King CR, Zavala F, Burton DR, Wilson IA, Rogers TF. Beutler N, et al. Among authors: locke e. PLoS Pathog. 2022 Mar 28;18(3):e1010409. doi: 10.1371/journal.ppat.1010409. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35344575 Free PMC article.
Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose-escalation, phase 1 trial in healthy malaria-naive adults.
van der Boor SC, Smit MJ, van Beek SW, Ramjith J, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Pickkers P, Wu Y, Locke E, Lee SM, Aponte J, King CR, Birkett AJ, Miura K, Ayorinde MA, Sauerwein RW, Ter Heine R, Ockenhouse CF, Bousema T, Jore MM, McCall MBB. van der Boor SC, et al. Among authors: locke e. Lancet Infect Dis. 2022 Nov;22(11):1596-1605. doi: 10.1016/S1473-3099(22)00428-5. Epub 2022 Aug 10. Lancet Infect Dis. 2022. PMID: 35963275 Free PMC article. Clinical Trial.
168 results