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SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade.
Romero OA, Vilarrubi A, Alburquerque-Bejar JJ, Gomez A, Andrades A, Trastulli D, Pros E, Setien F, Verdura S, Farré L, Martín-Tejera JF, Llabata P, Oaknin A, Saigi M, Piulats JM, Matias-Guiu X, Medina PP, Vidal A, Villanueva A, Sanchez-Cespedes M. Romero OA, et al. Among authors: llabata p. Nat Commun. 2021 Jul 14;12(1):4319. doi: 10.1038/s41467-021-24618-3. Nat Commun. 2021. PMID: 34262032 Free PMC article.
Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma.
Llabata P, Mitsuishi Y, Choi PS, Cai D, Francis JM, Torres-Diz M, Udeshi ND, Golomb L, Wu Z, Zhou J, Svinkina T, Aguilera-Jimenez E, Liu Y, Carr SA, Sanchez-Cespedes M, Meyerson M, Zhang X. Llabata P, et al. Mol Cancer Res. 2020 Apr;18(4):574-584. doi: 10.1158/1541-7786.MCR-19-0657. Epub 2019 Dec 20. Mol Cancer Res. 2020. PMID: 31862696 Free PMC article.
Involvement of the eIF2α Kinase GCN2 in UV-B Responses.
Llabata P, Richter J, Faus I, Słomiňska-Durdasiak K, Zeh LH, Gadea J, Hauser MT. Llabata P, et al. Front Plant Sci. 2019 Nov 28;10:1492. doi: 10.3389/fpls.2019.01492. eCollection 2019. Front Plant Sci. 2019. PMID: 31850012 Free PMC article.
MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer.
Alburquerque-Bejar JJ, Navajas-Chocarro P, Saigi M, Ferrero-Andres A, Morillas JM, Vilarrubi A, Gomez A, Mate JL, Munoz-Marmol AM, Romero OA, Blecua P, Davalos V, Esteller M, Pros E, Llabata P, Torres-Diz M, Esteve-Codina A, Sanchez-Cespedes M. Alburquerque-Bejar JJ, et al. Among authors: llabata p. Cell Rep Med. 2023 Apr 18;4(4):101006. doi: 10.1016/j.xcrm.2023.101006. Epub 2023 Apr 11. Cell Rep Med. 2023. PMID: 37044092 Free PMC article.