H3K27me3 is an epigenetic barrier while KDM6A overexpression improves nuclear reprogramming efficiency.
Zhou C, Wang Y, Zhang J, Su J, An Q, Liu X, Zhang M, Wang Y, Liu J, Zhang Y.
Zhou C, et al. Among authors: liu j, liu x.
FASEB J. 2019 Mar;33(3):4638-4652. doi: 10.1096/fj.201801887R. Epub 2019 Jan 23.
FASEB J. 2019.
PMID: 30673507
KDM6A overexpression enhanced the transcription of genes involved in cell adhesion and cellular metabolism and X-linked genes. Furthermore, we identified methyl-CpG-binding domain protein 3-like 2, which was reactivated by KDM6A, as a factor that is required for effective …
KDM6A overexpression enhanced the transcription of genes involved in cell adhesion and cellular metabolism and X-linked genes. Furthe …