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SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.
Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar MS, Liu WH, Gozdecka M, Metzakopian E, Toop HD, Dudek M, Robson SC, Hermida-Prado F, Yang YH, Babaei-Jadidi R, Garyfallos DA, Ponstingl H, Dias JML, Gallipoli P, Seiler M, Buonamici S, Vick B, Bannister AJ, Rad R, Prinjha RK, Marioni JC, Huntly B, Batson J, Morris JC, Pina C, Bradley A, Jeremias I, Bates DO, Yusa K, Kouzarides T, Vassiliou GS. Tzelepis K, et al. Among authors: liu wh. Nat Commun. 2018 Dec 19;9(1):5378. doi: 10.1038/s41467-018-07620-0. Nat Commun. 2018. PMID: 30568163 Free PMC article.
In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets.
Carlet M, Völse K, Vergalli J, Becker M, Herold T, Arner A, Senft D, Jurinovic V, Liu WH, Gao Y, Dill V, Fehse B, Baldus CD, Bastian L, Lenk L, Schewe DM, Bagnoli JW, Vick B, Schmid JP, Wilhelm A, Marschalek R, Jost PJ, Miething C, Riecken K, Schmidt-Supprian M, Binder V, Jeremias I. Carlet M, et al. Among authors: liu wh. Nat Commun. 2021 Sep 27;12(1):5655. doi: 10.1038/s41467-021-25963-z. Nat Commun. 2021. PMID: 34580292 Free PMC article.
Plasticity in growth behavior of patients' acute myeloid leukemia stem cells growing in mice.
Ebinger S, Zeller C, Carlet M, Senft D, Bagnoli JW, Liu WH, Rothenberg-Thurley M, Enard W, Metzeler KH, Herold T, Spiekermann K, Vick B, Jeremias I. Ebinger S, et al. Among authors: liu wh. Haematologica. 2020 Dec 1;105(12):2855-2860. doi: 10.3324/haematol.2019.226282. Haematologica. 2020. PMID: 33256387 Free PMC article. No abstract available.
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
Stief SM, Hanneforth AL, Weser S, Mattes R, Carlet M, Liu WH, Bartoschek MD, Domínguez Moreno H, Oettle M, Kempf J, Vick B, Ksienzyk B, Tizazu B, Rothenberg-Thurley M, Quentmeier H, Hiddemann W, Vosberg S, Greif PA, Metzeler KH, Schotta G, Bultmann S, Jeremias I, Leonhardt H, Spiekermann K. Stief SM, et al. Among authors: liu wh. Leukemia. 2020 Jan;34(1):50-62. doi: 10.1038/s41375-019-0497-6. Epub 2019 Jun 14. Leukemia. 2020. PMID: 31201358 Free PMC article.
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[No authors listed] [No authors listed] PMID: 32029508
965 results