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Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, Edelweiss E, Hu H, Weierstall U, Liu W, Batyuk A, Gordeliy V, Han GW, Sarret P, Katritch V, Borshchevskiy V, Cherezov V. Luginina A, et al. Among authors: liu w. Sci Adv. 2019 Oct 9;5(10):eaax2518. doi: 10.1126/sciadv.aax2518. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31633023 Free PMC article.
Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.
Zhang H, Unal H, Gati C, Han GW, Liu W, Zatsepin NA, James D, Wang D, Nelson G, Weierstall U, Sawaya MR, Xu Q, Messerschmidt M, Williams GJ, Boutet S, Yefanov OM, White TA, Wang C, Ishchenko A, Tirupula KC, Desnoyer R, Coe J, Conrad CE, Fromme P, Stevens RC, Katritch V, Karnik SS, Cherezov V. Zhang H, et al. Among authors: liu w. Cell. 2015 May 7;161(4):833-44. doi: 10.1016/j.cell.2015.04.011. Epub 2015 Apr 23. Cell. 2015. PMID: 25913193 Free PMC article.
Serial Femtosecond Crystallography of Membrane Proteins.
Zhu L, Weierstall U, Cherezov V, Liu W. Zhu L, et al. Among authors: liu w. Adv Exp Med Biol. 2016;922:151-160. doi: 10.1007/978-3-319-35072-1_11. Adv Exp Med Biol. 2016. PMID: 27553241 Free PMC article.
Structural basis for selectivity and diversity in angiotensin II receptors.
Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, Babaoglu K, Moore EL, Katz RD, Shipman JM, Garcia-Calvo M, Sharma S, Sheth P, Soisson SM, Stevens RC, Katritch V, Cherezov V. Zhang H, et al. Among authors: liu w. Nature. 2017 Apr 20;544(7650):327-332. doi: 10.1038/nature22035. Epub 2017 Apr 5. Nature. 2017. PMID: 28379944 Free PMC article.
Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor.
Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC. Audet M, et al. Among authors: liu w. Nat Chem Biol. 2019 Jan;15(1):11-17. doi: 10.1038/s41589-018-0160-y. Epub 2018 Dec 3. Nat Chem Biol. 2019. PMID: 30510194 Free PMC article.
XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity.
Johansson LC, Stauch B, McCorvy JD, Han GW, Patel N, Huang XP, Batyuk A, Gati C, Slocum ST, Li C, Grandner JM, Hao S, Olsen RHJ, Tribo AR, Zaare S, Zhu L, Zatsepin NA, Weierstall U, Yous S, Stevens RC, Liu W, Roth BL, Katritch V, Cherezov V. Johansson LC, et al. Among authors: liu w. Nature. 2019 May;569(7755):289-292. doi: 10.1038/s41586-019-1144-0. Epub 2019 Apr 24. Nature. 2019. PMID: 31019305 Free PMC article.
Structural basis of ligand recognition at the human MT1 melatonin receptor.
Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, Grant TD, Grandner JM, Shiriaeva A, Olsen RHJ, Tribo AR, Yous S, Stevens RC, Weierstall U, Katritch V, Roth BL, Liu W, Cherezov V. Stauch B, et al. Among authors: liu w. Nature. 2019 May;569(7755):284-288. doi: 10.1038/s41586-019-1141-3. Epub 2019 Apr 24. Nature. 2019. PMID: 31019306 Free PMC article.
Toward G protein-coupled receptor structure-based drug design using X-ray lasers.
Ishchenko A, Stauch B, Han GW, Batyuk A, Shiriaeva A, Li C, Zatsepin N, Weierstall U, Liu W, Nango E, Nakane T, Tanaka R, Tono K, Joti Y, Iwata S, Moraes I, Gati C, Cherezov V. Ishchenko A, et al. Among authors: liu w. IUCrJ. 2019 Oct 24;6(Pt 6):1106-1119. doi: 10.1107/S2052252519013137. eCollection 2019 Nov 1. IUCrJ. 2019. PMID: 31709066 Free PMC article.
Molecular basis for lipid recognition by the prostaglandin D2 receptor CRTH2.
Liu H, Deepak RNVK, Shiriaeva A, Gati C, Batyuk A, Hu H, Weierstall U, Liu W, Wang L, Cherezov V, Fan H, Zhang C. Liu H, et al. Among authors: liu w. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2102813118. doi: 10.1073/pnas.2102813118. Proc Natl Acad Sci U S A. 2021. PMID: 34341104 Free PMC article.
Structural basis for receptor selectivity and inverse agonism in S1P5 receptors.
Lyapina E, Marin E, Gusach A, Orekhov P, Gerasimov A, Luginina A, Vakhrameev D, Ergasheva M, Kovaleva M, Khusainov G, Khorn P, Shevtsov M, Kovalev K, Bukhdruker S, Okhrimenko I, Popov P, Hu H, Weierstall U, Liu W, Cho Y, Gushchin I, Rogachev A, Bourenkov G, Park S, Park G, Hyun HJ, Park J, Gordeliy V, Borshchevskiy V, Mishin A, Cherezov V. Lyapina E, et al. Among authors: liu w. Nat Commun. 2022 Aug 12;13(1):4736. doi: 10.1038/s41467-022-32447-1. Nat Commun. 2022. PMID: 35961984 Free PMC article.
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