Liu R - Search Results

1

Development of Bicyclo[3.1.0]hexane-Based A₃ Receptor Ligands: Closing the Gaps in the Structure-Affinity Relationships.

Lemmerhirt JP, Isaak A, Liu R, Kock M, Daniliuc CG, Jacobson KA, Heitman LH, Junker A. Lemmerhirt JP, et al. Among authors: liu r. Molecules. 2022 Mar 31;27(7):2283. doi: 10.3390/molecules27072283. Molecules. 2022. PMID: 35408685 Free PMC article.

2

Molecular Basis of Ligand Dissociation from the Adenosine A2A Receptor.

Guo D, Pan AC, Dror RO, Mocking T, Liu R, Heitman LH, Shaw DE, IJzerman AP. Guo D, et al. Among authors: liu r. Mol Pharmacol. 2016 May;89(5):485-91. doi: 10.1124/mol.115.102657. Epub 2016 Feb 12. Mol Pharmacol. 2016. PMID: 26873858

3

Long residence time adenosine A₁ receptor agonists produce sustained wash-resistant antilipolytic effect in rat adipocytes.

Yun Y, Chen J, Liu R, Chen W, Liu C, Wang R, Hou Z, Yu Z, Sun Y, IJzerman AP, Heitman LH, Yin X, Guo D. Yun Y, et al. Among authors: liu c, liu r. Biochem Pharmacol. 2019 Jun;164:45-52. doi: 10.1016/j.bcp.2019.03.032. Epub 2019 Mar 21. Biochem Pharmacol. 2019. PMID: 30905656

4

A multiple classifier system identifies novel cannabinoid CB2 receptor ligands.

Ruano-Ordás D, Burggraaff L, Liu R, van der Horst C, Heitman LH, Emmerich MTM, Mendez JR, Yevseyeva I, van Westen GJP. Ruano-Ordás D, et al. Among authors: liu r. J Cheminform. 2019 Nov 7;11(1):66. doi: 10.1186/s13321-019-0389-9. J Cheminform. 2019. PMID: 33430920 Free PMC article.

5

Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A_2A Receptor.

Amelia T, van Veldhoven JPD, Falsini M, Liu R, Heitman LH, van Westen GJP, Segala E, Verdon G, Cheng RKY, Cooke RM, van der Es D, IJzerman AP. Amelia T, et al. Among authors: liu r. J Med Chem. 2021 Apr 8;64(7):3827-3842. doi: 10.1021/acs.jmedchem.0c01856. Epub 2021 Mar 25. J Med Chem. 2021. PMID: 33764785 Free PMC article.

6

Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate Transporters.

Sijben HJ, Dall' Acqua L, Liu R, Jarret A, Christodoulaki E, Onstein S, Wolf G, Verburgt SJ, Le Dévédec SE, Wiedmer T, Superti-Furga G, IJzerman AP, Heitman LH. Sijben HJ, et al. Among authors: liu r. Front Pharmacol. 2022 May 23;13:872335. doi: 10.3389/fphar.2022.872335. eCollection 2022. Front Pharmacol. 2022. PMID: 35677430 Free PMC article.

7

Cancer-Associated Mutations of the Adenosine A_2A Receptor Have Diverse Influences on Ligand Binding and Receptor Functions.

Feng C, Wang X, Jespers W, Liu R, Zamarbide Losada SD, Gorostiola González M, van Westen GJP, Danen EHJ, Heitman LH. Feng C, et al. Among authors: liu r. Molecules. 2022 Jul 22;27(15):4676. doi: 10.3390/molecules27154676. Molecules. 2022. PMID: 35897852 Free PMC article.

8

Development of subtype-selective covalent ligands for the adenosine A_2B receptor by tuning the reactive group.

Beerkens BLH, Wang X, Avgeropoulou M, Adistia LN, van Veldhoven JPD, Jespers W, Liu R, Heitman LH, IJzerman AP, van der Es D. Beerkens BLH, et al. Among authors: liu r. RSC Med Chem. 2022 Jun 21;13(7):850-856. doi: 10.1039/d2md00132b. eCollection 2022 Jul 20. RSC Med Chem. 2022. PMID: 35923720 Free PMC article.

9

A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A₁ Receptor Using an Electrophilic Covalent Probe.

Beerkens BLH, Koç Ç, Liu R, Florea BI, Le Dévédec SE, Heitman LH, IJzerman AP, van der Es D. Beerkens BLH, et al. Among authors: liu r. ACS Chem Biol. 2022 Nov 18;17(11):3131-3139. doi: 10.1021/acschembio.2c00589. Epub 2022 Oct 24. ACS Chem Biol. 2022. PMID: 36279267 Free PMC article.

10

Microwave-Assisted Synthesis, Structure, and Preliminary Biological Evaluation of Novel 6-Methoxy-5,6-dihydro-5-azapurines.

Siutkina AI, Kalinina S, Liu R, Heitman LH, Junker A, Daniliuc CG, Kalinin DV. Siutkina AI, et al. Among authors: liu r. ACS Omega. 2023 Apr 5;8(15):14097-14112. doi: 10.1021/acsomega.3c00765. eCollection 2023 Apr 18. ACS Omega. 2023. PMID: 37091407 Free PMC article.

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