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Tead1 is essential for mitochondrial function in cardiomyocytes.
Liu R, Jagannathan R, Sun L, Li F, Yang P, Lee J, Negi V, Perez-Garcia EM, Shiva S, Yechoor VK, Moulik M. Liu R, et al. Am J Physiol Heart Circ Physiol. 2020 Jul 1;319(1):H89-H99. doi: 10.1152/ajpheart.00732.2019. Epub 2020 Jun 5. Am J Physiol Heart Circ Physiol. 2020. PMID: 32502376 Free PMC article.
Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy.
Liu R, Lee J, Kim BS, Wang Q, Buxton SK, Balasubramanyam N, Kim JJ, Dong J, Zhang A, Li S, Gupte AA, Hamilton DJ, Martin JF, Rodney GG, Coarfa C, Wehrens XH, Yechoor VK, Moulik M. Liu R, et al. JCI Insight. 2017 Sep 7;2(17):e93343. doi: 10.1172/jci.insight.93343. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878117 Free PMC article.
Tead1 is required for perinatal cardiomyocyte proliferation.
Liu R, Jagannathan R, Li F, Lee J, Balasubramanyam N, Kim BS, Yang P, Yechoor VK, Moulik M. Liu R, et al. PLoS One. 2019 Feb 27;14(2):e0212017. doi: 10.1371/journal.pone.0212017. eCollection 2019. PLoS One. 2019. PMID: 30811446 Free PMC article.
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