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W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway.
Li T, Lin GY, Zhong L, Zhou Y, Wang J, Zhu Y, Feng Y, Cai XQ, Liu Q, Nosjean O, Boutin JA, Renard P, Yang DH, Wang MW. Li T, et al. Among authors: liu q. Acta Pharmacol Sin. 2017 Jul;38(7):1024-1037. doi: 10.1038/aps.2017.15. Epub 2017 May 15. Acta Pharmacol Sin. 2017. PMID: 28502980 Free PMC article.
Cycloalkane analogues of sinefungin as EHMT1/2 inhibitors.
Liu Q, Cai X, Yang D, Chen Y, Wang Y, Shao L, Wang MW. Liu Q, et al. Bioorg Med Chem. 2017 Sep 1;25(17):4579-4594. doi: 10.1016/j.bmc.2017.06.032. Epub 2017 Jun 21. Bioorg Med Chem. 2017. PMID: 28739157
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