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REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.
Lee SH, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim S, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO. Lee SH, et al. Among authors: liu p. Nat Commun. 2020 Feb 19;11(1):965. doi: 10.1038/s41467-019-14143-9. Nat Commun. 2020. PMID: 32075961 Free PMC article.
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.
Sharma P, Abbasi C, Lazic S, Teng ACT, Wang D, Dubois N, Ignatchenko V, Wong V, Liu J, Araki T, Tiburcy M, Ackerley C, Zimmermann WH, Hamilton R, Sun Y, Liu PP, Keller G, Stagljar I, Scott IC, Kislinger T, Gramolini AO. Sharma P, et al. Among authors: liu pp, liu j. Nat Commun. 2015 Sep 25;6:8391. doi: 10.1038/ncomms9391. Nat Commun. 2015. PMID: 26403541 Free article.
Metformin increases degradation of phospholamban via autophagy in cardiomyocytes.
Teng AC, Miyake T, Yokoe S, Zhang L, Rezende LM Jr, Sharma P, MacLennan DH, Liu PP, Gramolini AO. Teng AC, et al. Among authors: liu pp. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7165-70. doi: 10.1073/pnas.1508815112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26040000 Free PMC article.
Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by alpha-crystallin-B.
Bousette N, Chugh S, Fong V, Isserlin R, Kim KH, Volchuk A, Backx PH, Liu P, Kislinger T, MacLennan DH, Emili A, Gramolini AO. Bousette N, et al. Among authors: liu p. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18481-6. doi: 10.1073/pnas.1013555107. Epub 2010 Oct 11. Proc Natl Acad Sci U S A. 2010. PMID: 20937869 Free PMC article.
Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.
Gramolini AO, Kislinger T, Alikhani-Koopaei R, Fong V, Thompson NJ, Isserlin R, Sharma P, Oudit GY, Trivieri MG, Fagan A, Kannan A, Higgins DG, Huedig H, Hess G, Arab S, Seidman JG, Seidman CE, Frey B, Perry M, Backx PH, Liu PP, MacLennan DH, Emili A. Gramolini AO, et al. Among authors: liu pp. Mol Cell Proteomics. 2008 Mar;7(3):519-33. doi: 10.1074/mcp.M700245-MCP200. Epub 2007 Nov 30. Mol Cell Proteomics. 2008. PMID: 18056057 Free article.
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