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Long noncoding RNA CDKN2B-AS1 interacts with transcription factor BCL11A to regulate progression of cerebral infarction through mediating MAP4K1 transcription.
Lei JJ, Li HQ, Mo ZH, Liu KJ, Zhu LJ, Li CY, Chen WL, Zhang L. Lei JJ, et al. FASEB J. 2019 Jun;33(6):7037-7048. doi: 10.1096/fj.201802252R. Epub 2019 Mar 14. FASEB J. 2019. PMID: 30870006
Collectively, our study provides evidence that CDKN2B-AS1 silencing could increase MAP4K1 expression to inhibit the CD4(+)CD25(+) T(reg)-cell proliferation by reducing enrichment of transcription factor BCL11A, thereby protecting against cerebral infarction progression, highlight …
Collectively, our study provides evidence that CDKN2B-AS1 silencing could increase MAP4K1 expression to inhibit the CD4(+)CD25(+) T(reg)-cel …
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