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Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia.
Park GH, Noh H, Shao Z, Ni P, Qin Y, Liu D, Beaudreault CP, Park JS, Abani CP, Park JM, Le DT, Gonzalez SZ, Guan Y, Cohen BM, McPhie DL, Coyle JT, Lanz TA, Xi HS, Yin C, Huang W, Kim HY, Chung S. Park GH, et al. Among authors: liu d. Nat Neurosci. 2020 Nov;23(11):1352-1364. doi: 10.1038/s41593-020-00724-1. Epub 2020 Oct 23. Nat Neurosci. 2020. PMID: 33097921 Free PMC article.
Caspr1 is a host receptor for meningitis-causing Escherichia coli.
Zhao WD, Liu DX, Wei JY, Miao ZW, Zhang K, Su ZK, Zhang XW, Li Q, Fang WG, Qin XX, Shang DS, Li B, Li QC, Cao L, Kim KS, Chen YH. Zhao WD, et al. Nat Commun. 2018 Jun 12;9(1):2296. doi: 10.1038/s41467-018-04637-3. Nat Commun. 2018. PMID: 29895952 Free PMC article.
Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development.
Liu D, Zinski A, Mishra A, Noh H, Park GH, Qin Y, Olorife O, Park JM, Abani CP, Park JS, Fung J, Sawaqed F, Coyle JT, Stahl E, Bendl J, Fullard JF, Roussos P, Zhang X, Stanton PK, Yin C, Huang W, Kim HY, Won H, Cho JH, Chung S. Liu D, et al. Mol Psychiatry. 2022 Oct;27(10):4218-4233. doi: 10.1038/s41380-022-01654-z. Epub 2022 Jun 14. Mol Psychiatry. 2022. PMID: 35701597
Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition.
Zhu Q, Mishra A, Park JS, Liu D, Le DT, Gonzalez SZ, Anderson-Crannage M, Park JM, Park GH, Tarbay L, Daneshvar K, Brandenburg M, Signoretti C, Zinski A, Gardner EJ, Zheng KL, Abani CP, Hu C, Beaudreault CP, Zhang XL, Stanton PK, Cho JH, Velíšek L, Velíšková J, Javed S, Leonard CS, Kim HY, Chung S. Zhu Q, et al. Among authors: liu d. Neuron. 2023 Mar 15;111(6):807-823.e7. doi: 10.1016/j.neuron.2022.12.014. Epub 2023 Jan 9. Neuron. 2023. PMID: 36626901 Free PMC article.
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