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A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans.
Sun EW, Iepsen EW, Pezos N, Lumsden AL, Martin AM, Schober G, Isaacs NJ, Rayner CK, Nguyen NQ, de Fontgalland D, Rabbitt P, Hollington P, Wattchow DA, Hansen T, Holm JC, Liou AP, Jackson VM, Torekov SS, Young RL, Keating DJ. Sun EW, et al. Among authors: liou ap. Gastroenterology. 2021 Aug;161(2):536-547.e2. doi: 10.1053/j.gastro.2021.04.014. Epub 2021 Apr 20. Gastroenterology. 2021. PMID: 33848536
Augmented capacity for peripheral serotonin release in human obesity.
Young RL, Lumsden AL, Martin AM, Schober G, Pezos N, Thazhath SS, Isaacs NJ, Cvijanovic N, Sun EWL, Wu T, Rayner CK, Nguyen NQ, Fontgalland D, Rabbitt P, Hollington P, Sposato L, Due SL, Wattchow DA, Liou AP, Jackson VM, Keating DJ. Young RL, et al. Among authors: liou ap. Int J Obes (Lond). 2018 Nov;42(11):1880-1889. doi: 10.1038/s41366-018-0047-8. Epub 2018 Mar 1. Int J Obes (Lond). 2018. PMID: 29568107
Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes.
Bahne E, Sun EWL, Young RL, Hansen M, Sonne DP, Hansen JS, Rohde U, Liou AP, Jackson ML, de Fontgalland D, Rabbitt P, Hollington P, Sposato L, Due S, Wattchow DA, Rehfeld JF, Holst JJ, Keating DJ, Vilsbøll T, Knop FK. Bahne E, et al. Among authors: liou ap. JCI Insight. 2018 Dec 6;3(23):e93936. doi: 10.1172/jci.insight.93936. JCI Insight. 2018. PMID: 30518693 Free PMC article. Clinical Trial.
Sugar Responses of Human Enterochromaffin Cells Depend on Gut Region, Sex, and Body Mass.
Lumsden AL, Martin AM, Sun EW, Schober G, Isaacs NJ, Pezos N, Wattchow DA, de Fontgalland D, Rabbitt P, Hollington P, Sposato L, Due SL, Rayner CK, Nguyen NQ, Liou AP, Jackson VM, Young RL, Keating DJ. Lumsden AL, et al. Among authors: liou ap. Nutrients. 2019 Jan 22;11(2):234. doi: 10.3390/nu11020234. Nutrients. 2019. PMID: 30678223 Free PMC article.
Latest approaches for the treatment of obesity.
Jackson VM, Breen DM, Fortin JP, Liou A, Kuzmiski JB, Loomis AK, Rives ML, Shah B, Carpino PA. Jackson VM, et al. Expert Opin Drug Discov. 2015;10(8):825-39. doi: 10.1517/17460441.2015.1044966. Epub 2015 May 12. Expert Opin Drug Discov. 2015. PMID: 25967138 Review.
GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans.
Patel S, Alvarez-Guaita A, Melvin A, Rimmington D, Dattilo A, Miedzybrodzka EL, Cimino I, Maurin AC, Roberts GP, Meek CL, Virtue S, Sparks LM, Parsons SA, Redman LM, Bray GA, Liou AP, Woods RM, Parry SA, Jeppesen PB, Kolnes AJ, Harding HP, Ron D, Vidal-Puig A, Reimann F, Gribble FM, Hulston CJ, Farooqi IS, Fafournoux P, Smith SR, Jensen J, Breen D, Wu Z, Zhang BB, Coll AP, Savage DB, O'Rahilly S. Patel S, et al. Among authors: liou ap. Cell Metab. 2019 Mar 5;29(3):707-718.e8. doi: 10.1016/j.cmet.2018.12.016. Epub 2019 Jan 10. Cell Metab. 2019. PMID: 30639358 Free PMC article.
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