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Nicotinamide for the treatment of heart failure with preserved ejection fraction.
Abdellatif M, Trummer-Herbst V, Koser F, Durand S, Adão R, Vasques-Nóvoa F, Freundt JK, Voglhuber J, Pricolo MR, Kasa M, Türk C, Aprahamian F, Herrero-Galán E, Hofer SJ, Pendl T, Rech L, Kargl J, Anto-Michel N, Ljubojevic-Holzer S, Schipke J, Brandenberger C, Auer M, Schreiber R, Koyani CN, Heinemann A, Zirlik A, Schmidt A, von Lewinski D, Scherr D, Rainer PP, von Maltzahn J, Mühlfeld C, Krüger M, Frank S, Madeo F, Eisenberg T, Prokesch A, Leite-Moreira AF, Lourenço AP, Alegre-Cebollada J, Kiechl S, Linke WA, Kroemer G, Sedej S. Abdellatif M, et al. Among authors: linke wa. Sci Transl Med. 2021 Feb 10;13(580):eabd7064. doi: 10.1126/scitranslmed.abd7064. Sci Transl Med. 2021. PMID: 33568522 Free PMC article.
Myocardial titin hypophosphorylation importantly contributes to heart failure with preserved ejection fraction in a rat metabolic risk model.
Hamdani N, Franssen C, Lourenço A, Falcão-Pires I, Fontoura D, Leite S, Plettig L, López B, Ottenheijm CA, Becher PM, González A, Tschöpe C, Díez J, Linke WA, Leite-Moreira AF, Paulus WJ. Hamdani N, et al. Among authors: linke wa. Circ Heart Fail. 2013 Nov;6(6):1239-49. doi: 10.1161/CIRCHEARTFAILURE.113.000539. Epub 2013 Sep 6. Circ Heart Fail. 2013. PMID: 24014826
Heart failure with preserved ejection fraction.
Gladden JD, Linke WA, Redfield MM. Gladden JD, et al. Among authors: linke wa. Pflugers Arch. 2014 Jun;466(6):1037-53. doi: 10.1007/s00424-014-1480-8. Epub 2014 Mar 25. Pflugers Arch. 2014. PMID: 24663384 Free PMC article. Review.
A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction.
Schwarzl M, Hamdani N, Seiler S, Alogna A, Manninger M, Reilly S, Zirngast B, Kirsch A, Steendijk P, Verderber J, Zweiker D, Eller P, Höfler G, Schauer S, Eller K, Maechler H, Pieske BM, Linke WA, Casadei B, Post H. Schwarzl M, et al. Among authors: linke wa. Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1407-18. doi: 10.1152/ajpheart.00542.2015. Epub 2015 Sep 4. Am J Physiol Heart Circ Physiol. 2015. PMID: 26342070 Free article.
Cardioprotection and lifespan extension by the natural polyamine spermidine.
Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Eisenberg T, et al. Among authors: linke wa. Nat Med. 2016 Dec;22(12):1428-1438. doi: 10.1038/nm.4222. Epub 2016 Nov 14. Nat Med. 2016. PMID: 27841876 Free PMC article.
Dietary spermidine for lowering high blood pressure.
Eisenberg T, Abdellatif M, Zimmermann A, Schroeder S, Pendl T, Harger A, Stekovic S, Schipke J, Magnes C, Schmidt A, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Carmona-Gutierrez D, Pietrocola F, Pieber TR, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F. Eisenberg T, et al. Among authors: linke wa. Autophagy. 2017 Apr 3;13(4):767-769. doi: 10.1080/15548627.2017.1280225. Epub 2017 Jan 24. Autophagy. 2017. PMID: 28118075 Free PMC article.
Stretch-induced compliance: a novel adaptive biological mechanism following acute cardiac load.
Leite-Moreira AM, Almeida-Coelho J, Neves JS, Pires AL, Ferreira-Martins J, Castro-Ferreira R, Ladeiras-Lopes R, Conceição G, Miranda-Silva D, Rodrigues P, Hamdani N, Herwig M, Falcão-Pires I, Paulus WJ, Linke WA, Lourenço AP, Leite-Moreira AF. Leite-Moreira AM, et al. Among authors: linke wa. Cardiovasc Res. 2018 Apr 1;114(5):656-667. doi: 10.1093/cvr/cvy026. Cardiovasc Res. 2018. PMID: 29401264
200 results