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IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.
Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO, Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC. Chan LC, et al. Among authors: lin x. J Clin Invest. 2019 Jul 15;129(8):3324-3338. doi: 10.1172/JCI126022. eCollection 2019 Jul 15. J Clin Invest. 2019. PMID: 31305264 Free PMC article.
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.
Luo X, Donnelly CR, Gong W, Heath BR, Hao Y, Donnelly LA, Moghbeli T, Tan YS, Lin X, Bellile E, Kansy BA, Carey TE, Brenner JC, Cheng L, Polverini PJ, Morgan MA, Wen H, Prince ME, Ferris RL, Xie Y, Young S, Wolf GT, Chen Q, Lei YL. Luo X, et al. Among authors: lin x. J Clin Invest. 2020 Apr 1;130(4):1635-1652. doi: 10.1172/JCI129497. J Clin Invest. 2020. PMID: 31874109 Free PMC article.
The E3 ligase TRAF6 regulates Akt ubiquitination and activation.
Yang WL, Wang J, Chan CH, Lee SW, Campos AD, Lamothe B, Hur L, Grabiner BC, Lin X, Darnay BG, Lin HK. Yang WL, et al. Among authors: lin hk, lin x. Science. 2009 Aug 28;325(5944):1134-8. doi: 10.1126/science.1175065. Science. 2009. PMID: 19713527 Free PMC article.
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