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Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses.
Wang M, Rousseau B, Qiu K, Huang G, Zhang Y, Su H, Le Bihan-Benjamin C, Khati I, Artz O, Foote MB, Cheng YY, Lee KH, Miao MZ, Sun Y, Bousquet PJ, Hilmi M, Dumas E, Hamy AS, Reyal F, Lin L, Armistead PM, Song W, Vargason A, Arthur JC, Liu Y, Guo J, Zhou X, Nguyen J, He Y, Ting JP, Anselmo AC, Huang L. Wang M, et al. Among authors: lin l. Nat Biotechnol. 2023 Sep 25. doi: 10.1038/s41587-023-01957-8. Online ahead of print. Nat Biotechnol. 2023. PMID: 37749267
A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
Ely ZA, Mathey-Andrews N, Naranjo S, Gould SI, Mercer KL, Newby GA, Cabana CM, Rideout WM 3rd, Jaramillo GC, Khirallah JM, Holland K, Randolph PB, Freed-Pastor WA, Davis JR, Kulstad Z, Westcott PMK, Lin L, Anzalone AV, Horton BL, Pattada NB, Shanahan SL, Ye Z, Spranger S, Xu Q, Sánchez-Rivera FJ, Liu DR, Jacks T. Ely ZA, et al. Among authors: lin l. Nat Biotechnol. 2024 Mar;42(3):424-436. doi: 10.1038/s41587-023-01783-y. Epub 2023 May 11. Nat Biotechnol. 2024. PMID: 37169967
Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer.
Lee MS, Dennis C, Naqvi I, Dailey L, Lorzadeh A, Ye G, Zaytouni T, Adler A, Hitchcock DS, Lin L, Hoffman MT, Bhuiyan AM, Barth JL, Machacek ME, Mino-Kenudson M, Dougan SK, Jadhav U, Clish CB, Kalaany NY. Lee MS, et al. Among authors: lin l. Nature. 2023 Apr;616(7956):339-347. doi: 10.1038/s41586-023-05891-2. Epub 2023 Mar 29. Nature. 2023. PMID: 36991126 Free PMC article.
Aminoacylation error correction.
Lin L, Hale SP, Schimmel P. Lin L, et al. Nature. 1996 Nov 7;384(6604):33-4. doi: 10.1038/384033b0. Nature. 1996. PMID: 8900273 No abstract available.
TaSRT2 recognizes a viral protein to activate host immunity by increasing histone acetylation.
Zhong K, Jiang Y, Hu H, Yuan B, Wu M, Tu A, Xu G, Cai L, Liu T, Gao S, Li L, Liao Q, Guo L, Xia Y, Liu P, Cheng Y, Lin L, Zhang C, Chen J, Yang J. Zhong K, et al. Among authors: lin l. Sci Bull (Beijing). 2024 Apr 27:S2095-9273(24)00313-X. doi: 10.1016/j.scib.2024.04.064. Online ahead of print. Sci Bull (Beijing). 2024. PMID: 38735788 No abstract available.
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