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A MIR17HG-derived long noncoding RNA provides an essential chromatin scaffold for protein interaction and myeloma growth.
Morelli E, Fulciniti M, Samur MK, Ribeiro CF, Wert-Lamas L, Henninger JE, Gullà A, Aktas-Samur A, Todoerti K, Talluri S, Park WD, Federico C, Scionti F, Amodio N, Bianchi G, Johnstone M, Liu N, Gramegna D, Maisano D, Russo NA, Lin C, Tai YT, Neri A, Chauhan D, Hideshima T, Shammas MA, Tassone P, Gryaznov S, Young RA, Anderson KC, Novina CD, Loda M, Munshi NC. Morelli E, et al. Among authors: lin c. Blood. 2023 Jan 26;141(4):391-405. doi: 10.1182/blood.2022016892. Blood. 2023. PMID: 36126301 Free PMC article.
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells.
Sigova AA, Mullen AC, Molinie B, Gupta S, Orlando DA, Guenther MG, Almada AE, Lin C, Sharp PA, Giallourakis CC, Young RA. Sigova AA, et al. Among authors: lin c. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2876-81. doi: 10.1073/pnas.1221904110. Epub 2013 Feb 4. Proc Natl Acad Sci U S A. 2013. PMID: 23382218 Free PMC article.
Models of human core transcriptional regulatory circuitries.
Saint-André V, Federation AJ, Lin CY, Abraham BJ, Reddy J, Lee TI, Bradner JE, Young RA. Saint-André V, et al. Genome Res. 2016 Mar;26(3):385-96. doi: 10.1101/gr.197590.115. Epub 2016 Feb 3. Genome Res. 2016. PMID: 26843070 Free PMC article.
Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity.
Sheppard HE, Dall'Agnese A, Park WD, Shamim MH, Dubrulle J, Johnson HL, Stossi F, Cogswell P, Sommer J, Levy J, Sharifnia T, Wawer MJ, Nabet B, Gray NS, Clemons PA, Schreiber SL, Workman P, Young RA, Lin CY. Sheppard HE, et al. Cell Rep Med. 2021 Jan 19;2(1):100188. doi: 10.1016/j.xcrm.2020.100188. eCollection 2021 Jan 19. Cell Rep Med. 2021. PMID: 33521702 Free PMC article.
c-Myc regulates transcriptional pause release.
Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, Sharp PA, Young RA. Rahl PB, et al. Among authors: lin cy. Cell. 2010 Apr 30;141(3):432-45. doi: 10.1016/j.cell.2010.03.030. Cell. 2010. PMID: 20434984 Free PMC article.
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