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Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.
Cancer Discov. 2021 Nov;11(11):2884-2903. doi: 10.1158/2159-8290.CD-20-1690. Epub 2021 May 21.
Cancer Discov. 2021.
PMID: 34021002
Free PMC article.
RAS-driven oncogenesis is supported by downstream antioxidant programs.
Lim JKM, Leprivier G, Sorensen PH.
Lim JKM, et al.
Mol Cell Oncol. 2019 Nov 10;7(1):1654814. doi: 10.1080/23723556.2019.1654814. eCollection 2020.
Mol Cell Oncol. 2019.
PMID: 31993493
Free PMC article.
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MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation.
Delaidelli A, Negri GL, Jan A, Jansonius B, El-Naggar A, Lim JKM, Khan D, Oo HZ, Carnie CJ, Remke M, Maris JM, Leprivier G, Sorensen PH.
Delaidelli A, et al. Among authors: lim jkm.
Cell Death Differ. 2017 Sep;24(9):1564-1576. doi: 10.1038/cdd.2017.79. Epub 2017 Jun 2.
Cell Death Differ. 2017.
PMID: 28574509
Free PMC article.
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Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
Lim JKM, Delaidelli A, Minaker SW, Zhang HF, Colovic M, Yang H, Negri GL, von Karstedt S, Lockwood WW, Schaffer P, Leprivier G, Sorensen PH.
Lim JKM, et al.
Proc Natl Acad Sci U S A. 2019 May 7;116(19):9433-9442. doi: 10.1073/pnas.1821323116. Epub 2019 Apr 18.
Proc Natl Acad Sci U S A. 2019.
PMID: 31000598
Free PMC article.
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The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma.
Ahmadov U, Picard D, Bartl J, Silginer M, Trajkovic-Arsic M, Qin N, Blümel L, Wolter M, Lim JKM, Pauck D, Winkelkotte AM, Melcher M, Langini M, Marquardt V, Sander F, Stefanski A, Steltgens S, Hassiepen C, Kaufhold A, Meyer FD, Seibt A, Kleinesudeik L, Hain A, Münk C, Knobbe-Thomsen CB, Schramm A, Fischer U, Leprivier G, Stühler K, Fulda S, Siveke JT, Distelmaier F, Borkhardt A, Weller M, Roth P, Reifenberger G, Remke M.
Ahmadov U, et al. Among authors: lim jkm.
Cell Death Dis. 2021 Sep 28;12(10):885. doi: 10.1038/s41419-021-04146-0.
Cell Death Dis. 2021.
PMID: 34584066
Free PMC article.
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mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism.
Levy T, Voeltzke K, Hruby L, Alasad K, Bas Z, Snaebjörnsson M, Marciano R, Scharov K, Planque M, Vriens K, Christen S, Funk CM, Hassiepen C, Kahler A, Heider B, Picard D, Lim JKM, Stefanski A, Bendrin K, Vargas-Toscano A, Kahlert UD, Stühler K, Remke M, Elkabets M, Grünewald TGP, Reichert AS, Fendt SM, Schulze A, Reifenberger G, Rotblat B, Leprivier G.
Levy T, et al. Among authors: lim jkm.
Nat Commun. 2024 May 14;15(1):4083. doi: 10.1038/s41467-024-48386-y.
Nat Commun. 2024.
PMID: 38744825
Free PMC article.
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Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation.
Müller F, Lim JKM, Bebber CM, Seidel E, Tishina S, Dahlhaus A, Stroh J, Beck J, Yapici FI, Nakayama K, Torres Fernández L, Brägelmann J, Leprivier G, von Karstedt S.
Müller F, et al. Among authors: lim jkm.
Cell Death Differ. 2023 Feb;30(2):442-456. doi: 10.1038/s41418-022-01096-8. Epub 2022 Nov 29.
Cell Death Differ. 2023.
PMID: 36443441
Free PMC article.
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The impact of oncogenic RAS on redox balance and implications for cancer development.
Lim JKM, Leprivier G.
Lim JKM, et al.
Cell Death Dis. 2019 Dec 18;10(12):955. doi: 10.1038/s41419-019-2192-y.
Cell Death Dis. 2019.
PMID: 31852884
Free PMC article.
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