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Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies.
Tobi EW, Juvinao-Quintero DL, Ronkainen J, Ott R, Alfano R, Canouil M, Geurtsen ML, Khamis A, Küpers LK, Lim IY, Perron P, Pesce G, Tuhkanen J, Starling AP, Andrew T, Binder E, Caiazzo R, Chan JKY, Gaillard R, Gluckman PD, Keikkala E, Karnani N, Mustaniemi S, Nawrot TS, Pattou F, Plusquin M, Raverdy V, Tan KH, Tzala E, Raikkonen K, Winkler C, Ziegler AG, Annesi-Maesano I, Bouchard L, Chong YS, Dabelea D, Felix JF, Heude B, Jaddoe VWV, Lahti J, Reimann B, Vääräsmäki M, Bonnefond A, Froguel P, Hummel S, Kajantie E, Jarvelin MR, Steegers-Theunissen RPM, Howe CG, Hivert MF, Sebert S. Tobi EW, et al. Among authors: lim iy. Diabetes Care. 2022 Mar 1;45(3):614-623. doi: 10.2337/dc21-1701. Diabetes Care. 2022. PMID: 35104326 Free PMC article.
Choice of surrogate tissue influences neonatal EWAS findings.
Lin X, Teh AL, Chen L, Lim IY, Tan PF, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Lee YS, Holbrook JD, Godfrey KM, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Karnani N. Lin X, et al. BMC Med. 2017 Dec 5;15(1):211. doi: 10.1186/s12916-017-0970-x. BMC Med. 2017. PMID: 29202839 Free PMC article.
Dichotomy in the Impact of Elevated Maternal Glucose Levels on Neonatal Epigenome.
Lim IY, Lin X, Teh AL, Wu Y, Chen L, He M, Chan SY, MacIsaac JL, Chan JKY, Tan KH, Chong MFF, Kobor MS, Godfrey KM, Meaney MJ, Lee YS, Eriksson JG, Gluckman PD, Chong YS, Karnani N. Lim IY, et al. J Clin Endocrinol Metab. 2022 Feb 17;107(3):e1277-e1292. doi: 10.1210/clinem/dgab710. J Clin Endocrinol Metab. 2022. PMID: 34633450 Free PMC article.
Integrative multi-omics database (iMOMdb) of Asian pregnant women.
Pan H, Tan PF, Lim IY, Huan J, Teh AL, Chen L, Gong M, Tin F, Mir SA, Narasimhan K, Chan JKY, Tan KH, Kobor MS, Meikle PJ, Wenk MR, Chong YS, Eriksson JG, Gluckman PD, Karnani N. Pan H, et al. Hum Mol Genet. 2022 Sep 10;31(18):3051-3067. doi: 10.1093/hmg/ddac079. Hum Mol Genet. 2022. PMID: 35445712 Free PMC article.
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome.
Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group. Lin X, et al. BMC Med. 2017 Mar 7;15(1):50. doi: 10.1186/s12916-017-0800-1. BMC Med. 2017. PMID: 28264723 Free PMC article.
712 results