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2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer.
Blomme A, Ford CA, Mui E, Patel R, Ntala C, Jamieson LE, Planque M, McGregor GH, Peixoto P, Hervouet E, Nixon C, Salji M, Gaughan L, Markert E, Repiscak P, Sumpton D, Blanco GR, Lilla S, Kamphorst JJ, Graham D, Faulds K, MacKay GM, Fendt SM, Zanivan S, Leung HY. Blomme A, et al. Among authors: lilla s. Nat Commun. 2020 May 19;11(1):2508. doi: 10.1038/s41467-020-16126-7. Nat Commun. 2020. PMID: 32427840 Free PMC article.
Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.
Hernandez-Fernaud JR, Ruengeler E, Casazza A, Neilson LJ, Pulleine E, Santi A, Ismail S, Lilla S, Dhayade S, MacPherson IR, McNeish I, Ennis D, Ali H, Kugeratski FG, Al Khamici H, van den Biggelaar M, van den Berghe PV, Cloix C, McDonald L, Millan D, Hoyle A, Kuchnio A, Carmeliet P, Valenzuela SM, Blyth K, Yin H, Mazzone M, Norman JC, Zanivan S. Hernandez-Fernaud JR, et al. Among authors: lilla s. Nat Commun. 2017 Feb 15;8:14206. doi: 10.1038/ncomms14206. Nat Commun. 2017. PMID: 28198360 Free PMC article.
Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.
Port J, Muthalagu N, Raja M, Ceteci F, Monteverde T, Kruspig B, Hedley A, Kalna G, Lilla S, Neilson L, Brucoli M, Gyuraszova K, Tait-Mulder J, Mezna M, Svambaryte S, Bryson A, Sumpton D, McVie A, Nixon C, Drysdale M, Esumi H, Murray GI, Sansom OJ, Zanivan SR, Murphy DJ. Port J, et al. Among authors: lilla s. Cancer Discov. 2018 May;8(5):632-647. doi: 10.1158/2159-8290.CD-17-0533. Epub 2018 Mar 2. Cancer Discov. 2018. PMID: 29500295 Free PMC article.
Fam49/CYRI interacts with Rac1 and locally suppresses protrusions.
Fort L, Batista JM, Thomason PA, Spence HJ, Whitelaw JA, Tweedy L, Greaves J, Martin KJ, Anderson KI, Brown P, Lilla S, Neilson MP, Tafelmeyer P, Zanivan S, Ismail S, Bryant DM, Tomkinson NCO, Chamberlain LH, Mastick GS, Insall RH, Machesky LM. Fort L, et al. Among authors: lilla s. Nat Cell Biol. 2018 Oct;20(10):1159-1171. doi: 10.1038/s41556-018-0198-9. Epub 2018 Sep 24. Nat Cell Biol. 2018. PMID: 30250061 Free PMC article.
Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling.
Kugeratski FG, Atkinson SJ, Neilson LJ, Lilla S, Knight JRP, Serneels J, Juin A, Ismail S, Bryant DM, Markert EK, Machesky LM, Mazzone M, Sansom OJ, Zanivan S. Kugeratski FG, et al. Among authors: lilla s. Sci Signal. 2019 Feb 5;12(567):eaan8247. doi: 10.1126/scisignal.aan8247. Sci Signal. 2019. PMID: 30723174 Free PMC article.
CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors.
Whitelaw JA, Lilla S, Paul NR, Fort L, Zanivan S, Machesky LM. Whitelaw JA, et al. Among authors: lilla s. Commun Integr Biol. 2019 Jul 23;12(1):112-118. doi: 10.1080/19420889.2019.1643665. eCollection 2019. Commun Integr Biol. 2019. PMID: 31413787 Free PMC article.
BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration.
Loveridge CJ, Slater S, Campbell KJ, Nam NA, Knight J, Ahmad I, Hedley A, Lilla S, Repiscak P, Patel R, Salji M, Fleming J, Mitchell L, Nixon C, Strathdee D, Neilson M, Ntala C, Bryson S, Zanivan S, Edwards J, Robson CN, Goodyear CS, Blyth K, Leung HY. Loveridge CJ, et al. Among authors: lilla s. Oncogene. 2020 Feb;39(8):1797-1806. doi: 10.1038/s41388-019-1106-x. Epub 2019 Nov 18. Oncogene. 2020. PMID: 31740786 Free PMC article.
74 results