Light SH - Search Results

1

Bifidobacteria metabolize lactulose to optimize gut metabolites and prevent systemic infection in patients with liver disease.

Odenwald MA, Lin H, Lehmann C, Dylla NP, Cole CG, Mostad JD, Pappas TE, Ramaswamy R, Moran A, Hutchison AL, Stutz MR, Dela Cruz M, Adler E, Boissiere J, Khalid M, Cantoral J, Haro F, Oliveira RA, Waligurski E, Cotter TG, Light SH, Beavis KG, Sundararajan A, Sidebottom AM, Reddy KG, Paul S, Pillai A, Te HS, Rinella ME, Charlton MR, Pamer EG, Aronsohn AI. Odenwald MA, et al. Among authors: light sh. Nat Microbiol. 2023 Nov;8(11):2033-2049. doi: 10.1038/s41564-023-01493-w. Epub 2023 Oct 16. Nat Microbiol. 2023. PMID: 37845315 Free PMC article.

2

The diversity of allosteric controls at the gateway to aromatic amino acid biosynthesis.

Light SH, Anderson WF. Light SH, et al. Protein Sci. 2013 Apr;22(4):395-404. doi: 10.1002/pro.2233. Epub 2013 Mar 8. Protein Sci. 2013. PMID: 23400945 Free PMC article. Review.

3

Bacterial Microcompartments Coupled with Extracellular Electron Transfer Drive the Anaerobic Utilization of Ethanolamine in Listeria monocytogenes.

Zeng Z, Boeren S, Bhandula V, Light SH, Smid EJ, Notebaart RA, Abee T. Zeng Z, et al. Among authors: light sh. mSystems. 2021 Apr 13;6(2):e01349-20. doi: 10.1128/mSystems.01349-20. mSystems. 2021. PMID: 33850044 Free PMC article.

4

Post-translational flavinylation is associated with diverse extracytosolic redox functionalities throughout bacterial life.

Méheust R, Huang S, Rivera-Lugo R, Banfield JF, Light SH. Méheust R, et al. Among authors: light sh. Elife. 2021 May 25;10:e66878. doi: 10.7554/eLife.66878. Elife. 2021. PMID: 34032212 Free PMC article.

5

Reassessing the type I dehydroquinate dehydratase catalytic triad: kinetic and structural studies of Glu86 mutants.

Light SH, Anderson WF, Lavie A. Light SH, et al. Protein Sci. 2013 Apr;22(4):418-24. doi: 10.1002/pro.2218. Epub 2013 Feb 11. Protein Sci. 2013. PMID: 23341204 Free PMC article.

6

Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus.

Lee H, Ren J, Nocadello S, Rice AJ, Ojeda I, Light S, Minasov G, Vargas J, Nagarathnam D, Anderson WF, Johnson ME. Lee H, et al. Antiviral Res. 2017 Mar;139:49-58. doi: 10.1016/j.antiviral.2016.12.016. Epub 2016 Dec 26. Antiviral Res. 2017. PMID: 28034741 Free PMC article.

7

Stickland metabolism in the gut.

Little AS, Light SH. Little AS, et al. Among authors: light sh. Nat Microbiol. 2022 May;7(5):603-604. doi: 10.1038/s41564-022-01115-x. Nat Microbiol. 2022. PMID: 35505246 No abstract available.

8

Distinct Energy-Coupling Factor Transporter Subunits Enable Flavin Acquisition and Extracytosolic Trafficking for Extracellular Electron Transfer in Listeria monocytogenes.

Rivera-Lugo R, Huang S, Lee F, Méheust R, Iavarone AT, Sidebottom AM, Oldfield E, Portnoy DA, Light SH. Rivera-Lugo R, et al. Among authors: light sh. mBio. 2023 Feb 28;14(1):e0308522. doi: 10.1128/mbio.03085-22. Epub 2023 Feb 6. mBio. 2023. PMID: 36744898 Free PMC article.

9

Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration.

Little AS, Younker IT, Schechter MS, Bernardino PN, Méheust R, Stemczynski J, Scorza K, Mullowney MW, Sharan D, Waligurski E, Smith R, Ramanswamy R, Leiter W, Moran D, McMillin M, Odenwald MA, Iavarone AT, Sidebottom AM, Sundararajan A, Pamer EG, Eren AM, Light SH. Little AS, et al. Among authors: light sh. Nat Microbiol. 2024 Jan;9(1):55-69. doi: 10.1038/s41564-023-01560-2. Epub 2024 Jan 4. Nat Microbiol. 2024. PMID: 38177297

10

Structure to function of an α-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis.

Light SH, Cahoon LA, Halavaty AS, Freitag NE, Anderson WF. Light SH, et al. Nat Microbiol. 2016 Nov 7;2:16202. doi: 10.1038/nmicrobiol.2016.202. Nat Microbiol. 2016. PMID: 27819654

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