Lieshout R - Search Results

1

Label-Free Imaging Analysis of Patient-Derived Cholangiocarcinoma Organoids after Sorafenib Treatment.

Koch M, Nickel S, Lieshout R, Lissek SM, Leskova M, van der Laan LJW, Verstegen MMA, Christ B, Pampaloni F. Koch M, et al. Among authors: lieshout r. Cells. 2022 Nov 15;11(22):3613. doi: 10.3390/cells11223613. Cells. 2022. PMID: 36429040 Free PMC article.

2

Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth.

Li M, Wang L, Wang Y, Zhang S, Zhou G, Lieshout R, Ma B, Liu J, Qu C, Verstegen MMA, Sprengers D, Kwekkeboom J, van der Laan LJW, Cao W, Peppelenbosch MP, Pan Q. Li M, et al. Among authors: lieshout r. Cells. 2020 Jan 4;9(1):121. doi: 10.3390/cells9010121. Cells. 2020. PMID: 31947947 Free PMC article.

3

Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells.

Zhou G, Lieshout R, van Tienderen GS, de Ruiter V, van Royen ME, Boor PPC, Magré L, Desai J, Köten K, Kan YY, Ge Z, Campos Carrascosa L, Geuijen C, Sprengers D, van der Laan LJW, Verstegen MMA, Kwekkeboom J. Zhou G, et al. Among authors: lieshout r. Br J Cancer. 2022 Sep;127(4):649-660. doi: 10.1038/s41416-022-01839-x. Epub 2022 May 21. Br J Cancer. 2022. PMID: 35597867 Free PMC article.

4

Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification.

Lieshout R, Faria AVS, Peppelenbosch MP, van der Laan LJW, Verstegen MMA, Fuhler GM. Lieshout R, et al. Mol Med. 2022 Jun 28;28(1):74. doi: 10.1186/s10020-022-00498-1. Mol Med. 2022. PMID: 35764936 Free PMC article.

5

From organoids to organs: Bioengineering liver grafts from hepatic stem cells and matrix.

Willemse J, Lieshout R, van der Laan LJW, Verstegen MMA. Willemse J, et al. Among authors: lieshout r. Best Pract Res Clin Gastroenterol. 2017 Apr;31(2):151-159. doi: 10.1016/j.bpg.2017.03.003. Epub 2017 Apr 12. Best Pract Res Clin Gastroenterol. 2017. PMID: 28624103 Review.

6

Experimental models to unravel the molecular pathogenesis, cell of origin and stem cell properties of cholangiocarcinoma.

Vicent S, Lieshout R, Saborowski A, Verstegen MMA, Raggi C, Recalcati S, Invernizzi P, van der Laan LJW, Alvaro D, Calvisi DF, Cardinale V. Vicent S, et al. Among authors: lieshout r. Liver Int. 2019 May;39 Suppl 1:79-97. doi: 10.1111/liv.14094. Liver Int. 2019. PMID: 30851232 Free article. Review.

7

Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro.

Roos FJM, Wu H, Willemse J, Lieshout R, Albarinos LAM, Kan YY, Poley JW, Bruno MJ, de Jonge J, Bártfai R, Marks H, IJzermans JNM, Verstegen MMA, van der Laan LJW. Roos FJM, et al. Among authors: lieshout r. Clin Transl Med. 2021 Dec;11(12):e566. doi: 10.1002/ctm2.566. Clin Transl Med. 2021. PMID: 34954911 Free PMC article.

8

Cholangiocarcinoma cell proliferation is enhanced in primary sclerosing cholangitis: A role for IL-17A.

Lieshout R, Kamp EJCA, Verstegen MMA, Doukas M, Dinjens WNM, Köten K, IJzermans JNM, Bruno MJ, Peppelenbosch MP, van der Laan LJW, de Vries AC. Lieshout R, et al. Int J Cancer. 2023 Jun 15;152(12):2607-2614. doi: 10.1002/ijc.34350. Epub 2022 Nov 17. Int J Cancer. 2023. PMID: 36346104

9

Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition.

van Tienderen GS, Rosmark O, Lieshout R, Willemse J, de Weijer F, Elowsson Rendin L, Westergren-Thorsson G, Doukas M, Groot Koerkamp B, van Royen ME, van der Laan LJ, Verstegen MM. van Tienderen GS, et al. Among authors: lieshout r. Acta Biomater. 2023 Mar 1;158:115-131. doi: 10.1016/j.actbio.2022.11.038. Epub 2022 Nov 23. Acta Biomater. 2023. PMID: 36427688

10

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.

Broutier L, Mastrogiovanni G, Verstegen MM, Francies HE, Gavarró LM, Bradshaw CR, Allen GE, Arnes-Benito R, Sidorova O, Gaspersz MP, Georgakopoulos N, Koo BK, Dietmann S, Davies SE, Praseedom RK, Lieshout R, IJzermans JNM, Wigmore SJ, Saeb-Parsy K, Garnett MJ, van der Laan LJ, Huch M. Broutier L, et al. Among authors: lieshout r. Nat Med. 2017 Dec;23(12):1424-1435. doi: 10.1038/nm.4438. Epub 2017 Nov 13. Nat Med. 2017. PMID: 29131160 Free PMC article.

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