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Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists.
Bioorg Med Chem. 2015 Jul 15;23(14):3933-7. doi: 10.1016/j.bmc.2014.12.011. Epub 2014 Dec 17.
Bioorg Med Chem. 2015.
PMID: 25583099
Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist.
Jensen AA, McCorvy JD, Leth-Petersen S, Bundgaard C, Liebscher G, Kenakin TP, Bräuner-Osborne H, Kehler J, Kristensen JL.
Jensen AA, et al.
J Pharmacol Exp Ther. 2017 Jun;361(3):441-453. doi: 10.1124/jpet.117.239905. Epub 2017 Mar 30.
J Pharmacol Exp Ther. 2017.
PMID: 28360333
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The selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH.
Jensen AA, Halberstadt AL, Märcher-Rørsted E, Odland AU, Chatha M, Speth N, Liebscher G, Hansen M, Bräuner-Osborne H, Palner M, Andreasen JT, Kristensen JL.
Jensen AA, et al.
Biochem Pharmacol. 2020 Jul;177:113979. doi: 10.1016/j.bcp.2020.113979. Epub 2020 Apr 13.
Biochem Pharmacol. 2020.
PMID: 32298690
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The SZT2 Interactome Unravels New Functions of the KICSTOR Complex.
Cattelani C, Lesiak D, Liebscher G, Singer II, Stasyk T, Wallnöfer MH, Heberle AM, Corti C, Hess MW, Pfaller K, Kwiatkowski M, Pramstaller PP, Hicks AA, Thedieck K, Müller T, Huber LA, Eca Guimaraes de Araujo M.
Cattelani C, et al.
Cells. 2021 Oct 9;10(10):2711. doi: 10.3390/cells10102711.
Cells. 2021.
PMID: 34685691
Free PMC article.
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Lysosomal size matters.
de Araujo MEG, Liebscher G, Hess MW, Huber LA.
de Araujo MEG, et al.
Traffic. 2020 Jan;21(1):60-75. doi: 10.1111/tra.12714. Epub 2019 Dec 6.
Traffic. 2020.
PMID: 31808235
Free PMC article.
Review.
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Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol-3,5-bisphosphate.
Yordanov TE, Hipolito VEB, Liebscher G, Vogel GF, Stasyk T, Herrmann C, Geley S, Teis D, Botelho RJ, Hess MW, Huber LA.
Yordanov TE, et al.
Traffic. 2019 Sep;20(9):674-696. doi: 10.1111/tra.12679.
Traffic. 2019.
PMID: 31314175
Free PMC article.
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Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice.
Heine M, Fischer AW, Schlein C, Jung C, Straub LG, Gottschling K, Mangels N, Yuan Y, Nilsson SK, Liebscher G, Chen O, Schreiber R, Zechner R, Scheja L, Heeren J.
Heine M, et al.
Cell Metab. 2018 Oct 2;28(4):644-655.e4. doi: 10.1016/j.cmet.2018.06.020. Epub 2018 Jul 19.
Cell Metab. 2018.
PMID: 30033199
Free article.
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