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STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling.
Arimoto KI, Löchte S, Stoner SA, Burkart C, Zhang Y, Miyauchi S, Wilmes S, Fan JB, Heinisch JJ, Li Z, Yan M, Pellegrini S, Colland F, Piehler J, Zhang DE. Arimoto KI, et al. Among authors: li z. Nat Struct Mol Biol. 2017 Mar;24(3):279-289. doi: 10.1038/nsmb.3378. Epub 2017 Feb 6. Nat Struct Mol Biol. 2017. PMID: 28165510 Free PMC article.
ISG15 deficiency and increased viral resistance in humans but not mice.
Speer SD, Li Z, Buta S, Payelle-Brogard B, Qian L, Vigant F, Rubino E, Gardner TJ, Wedeking T, Hermann M, Duehr J, Sanal O, Tezcan I, Mansouri N, Tabarsi P, Mansouri D, Francois-Newton V, Daussy CF, Rodriguez MR, Lenschow DJ, Freiberg AN, Tortorella D, Piehler J, Lee B, García-Sastre A, Pellegrini S, Bogunovic D. Speer SD, et al. Among authors: li z. Nat Commun. 2016 May 19;7:11496. doi: 10.1038/ncomms11496. Nat Commun. 2016. PMID: 27193971 Free PMC article.
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