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Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Wang JL, Dou XD, Cheng J, Gao MX, Xu GF, Ding W, Ding JH, Li Y, Wang SH, Ji ZW, Zhao XY, Huo TY, Zhang CF, Liu YM, Sha XY, Gao JR, Zhang WH, Hao Y, Zhang C, Sun JP, Jiao N, Yu X. Wang JL, et al. Among authors: li y. Nat Metab. 2023 Oct;5(10):1726-1746. doi: 10.1038/s42255-023-00899-4. Epub 2023 Sep 28. Nat Metab. 2023. PMID: 37770763
Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Yang Z, Wang JY, Yang F, Zhu KK, Wang GP, Guan Y, Ning SL, Lu Y, Li Y, Zhang C, Zheng Y, Zhou SH, Wang XW, Wang MW, Xiao P, Yi F, Zhang C, Zhang PJ, Xu F, Liu BH, Zhang H, Yu X, Gao N, Sun JP. Yang Z, et al. Among authors: li y. Nat Chem Biol. 2024 Apr;20(4):484-492. doi: 10.1038/s41589-023-01456-6. Epub 2023 Nov 9. Nat Chem Biol. 2024. PMID: 37945893
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