Li Y - Search Results

1

Secondary-structure characterization of two proficient kinase deoxyribozymes.

Achenbach JC, Jeffries GA, McManus SA, Billen LP, Li Y. Achenbach JC, et al. Among authors: li y. Biochemistry. 2005 Mar 15;44(10):3765-74. doi: 10.1021/bi0483054. Biochemistry. 2005. PMID: 15751953

2

Sequence diversity, metal specificity, and catalytic proficiency of metal-dependent phosphorylating DNA enzymes.

Wang W, Billen LP, Li Y. Wang W, et al. Among authors: li y. Chem Biol. 2002 Apr;9(4):507-17. doi: 10.1016/s1074-5521(02)00127-8. Chem Biol. 2002. PMID: 11983339

3

An efficient RNA-cleaving DNA enzyme that synchronizes catalysis with fluorescence signaling.

Mei SH, Liu Z, Brennan JD, Li Y. Mei SH, et al. Among authors: li y. J Am Chem Soc. 2003 Jan 15;125(2):412-20. doi: 10.1021/ja0281232. J Am Chem Soc. 2003. PMID: 12517153

4

Dinucleotide junction cleavage versatility of 8-17 deoxyribozyme.

Cruz RP, Withers JB, Li Y. Cruz RP, et al. Among authors: li y. Chem Biol. 2004 Jan;11(1):57-67. doi: 10.1016/j.chembiol.2003.12.012. Chem Biol. 2004. PMID: 15112995 Free article.

5

Tracing sequence diversity change of RNA-cleaving deoxyribozymes under increasing selection pressure during in vitro selection.

Schlosser K, Li Y. Schlosser K, et al. Among authors: li y. Biochemistry. 2004 Aug 3;43(30):9695-707. doi: 10.1021/bi049757j. Biochemistry. 2004. PMID: 15274624

6

DNAzymes: from creation in vitro to application in vivo.

Achenbach JC, Chiuman W, Cruz RP, Li Y. Achenbach JC, et al. Among authors: li y. Curr Pharm Biotechnol. 2004 Aug;5(4):321-36. doi: 10.2174/1389201043376751. Curr Pharm Biotechnol. 2004. PMID: 15320762 Review.

7

Synthesis and characterization of topologically linked single-stranded DNA rings.

Billen LP, Li Y. Billen LP, et al. Among authors: li y. Bioorg Chem. 2004 Dec;32(6):582-98. doi: 10.1016/j.bioorg.2004.06.010. Bioorg Chem. 2004. PMID: 15530998

8

Diverse evolutionary trajectories characterize a community of RNA-cleaving deoxyribozymes: a case study into the population dynamics of in vitro selection.

Schlosser K, Li Y. Schlosser K, et al. Among authors: li y. J Mol Evol. 2005 Aug;61(2):192-206. doi: 10.1007/s00239-004-0346-7. Epub 2005 Jun 27. J Mol Evol. 2005. PMID: 16007486

9

Characterizing the secondary structure and identifying functionally essential nucleotides of pH6DZ1, a fluorescence-signaling and RNA-cleaving deoxyribozyme.

Shen Y, Brennan JD, Li Y. Shen Y, et al. Among authors: li y. Biochemistry. 2005 Sep 13;44(36):12066-76. doi: 10.1021/bi050746f. Biochemistry. 2005. PMID: 16142904

10

Characterization of a catalytically efficient acidic RNA-cleaving deoxyribozyme.

Kandadai SA, Li Y. Kandadai SA, et al. Among authors: li y. Nucleic Acids Res. 2006 Jan 3;33(22):7164-75. doi: 10.1093/nar/gki1013. Print 2005. Nucleic Acids Res. 2006. PMID: 16391005 Free PMC article.

We previously demonstrated--through the isolation of RNA-cleaving deoxyribozymes by in vitro selection that are catalytically active in highly acidic solutions--that DNA, despite its chemical simplicity, could perform catalysis under challenging chemical conditions [Liu,Z., Mei,S …

We previously demonstrated--through the isolation of RNA-cleaving deoxyribozymes by in vitro selection that are catalytically active in high …

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