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Plasma proteomics reveals early, broad release of chemokine, cytokine, TNF, and interferon mediators following trauma with delayed increases in a subset of chemokines and cytokines in patients that remain critically ill.
Bonaroti J, Billiar I, Moheimani H, Wu J, Namas R, Li S, Kar UK, Vodovotz Y, Neal MD, Sperry JL, Billiar TR. Bonaroti J, et al. Among authors: li s. Front Immunol. 2022 Nov 30;13:1038086. doi: 10.3389/fimmu.2022.1038086. eCollection 2022. Front Immunol. 2022. PMID: 36532045 Free PMC article.
Prehospital synergy: Tranexamic acid and blood transfusion in patients at risk for hemorrhage.
Deeb AP, Hoteit L, Li S, Guyette FX, Eastridge BJ, Nirula R, Vercruysse GA, O'Keeffe T, Joseph B, Neal MD, Sperry JL, Brown JB. Deeb AP, et al. Among authors: li s. J Trauma Acute Care Surg. 2022 Jul 1;93(1):52-58. doi: 10.1097/TA.0000000000003620. Epub 2022 Apr 8. J Trauma Acute Care Surg. 2022. PMID: 35393385 Free PMC article. Clinical Trial.
Association Between Time to Source Control in Sepsis and 90-Day Mortality.
Reitz KM, Kennedy J, Li SR, Handzel R, Tonetti DA, Neal MD, Zuckerbraun BS, Hall DE, Sperry JL, Angus DC, Tzeng E, Seymour CW. Reitz KM, et al. Among authors: li sr. JAMA Surg. 2022 Sep 1;157(9):817-826. doi: 10.1001/jamasurg.2022.2761. JAMA Surg. 2022. PMID: 35830181 Free PMC article.
High Dimensional Multiomics Reveals Unique Characteristics of Early Plasma Administration in Polytrauma Patients With TBI.
Wu J, Moheimani H, Li S, Kar UK, Bonaroti J, Miller RS, Daley BJ, Harbrecht BG, Claridge JA, Gruen DS, Phelan HA, Guyette FX, Neal MD, Das J, Sperry JL, Billiar TR. Wu J, et al. Among authors: li s. Ann Surg. 2022 Oct 1;276(4):673-683. doi: 10.1097/SLA.0000000000005610. Epub 2022 Jul 19. Ann Surg. 2022. PMID: 35861072 Free PMC article.
Multi-Omic Admission-Based Prognostic Biomarkers Identified by Machine Learning Algorithms Predict Patient Recovery and 30-Day Survival in Trauma Patients.
Abdelhamid SS, Scioscia J, Vodovotz Y, Wu J, Rosengart A, Sung E, Rahman S, Voinchet R, Bonaroti J, Li S, Darby JL, Kar UK, Neal MD, Sperry J, Das J, Billiar TR. Abdelhamid SS, et al. Among authors: li s. Metabolites. 2022 Aug 23;12(9):774. doi: 10.3390/metabo12090774. Metabolites. 2022. PMID: 36144179 Free PMC article.
High-dimensional proteomics identifies organ injury patterns associated with outcomes in human trauma.
Li SR, Moheimani H, Herzig B, Kail M, Krishnamoorthi N, Wu J, Abdelhamid S, Scioscia J, Sung E, Rosengart A, Bonaroti J, Johansson PI, Stensballe J, Neal MD, Das J, Kar U, Sperry J, Billiar TR. Li SR, et al. J Trauma Acute Care Surg. 2023 Jun 1;94(6):803-813. doi: 10.1097/TA.0000000000003880. Epub 2023 Feb 13. J Trauma Acute Care Surg. 2023. PMID: 36787435 Review.
Prehospital tranexamic acid is associated with a dose-dependent decrease in syndecan-1 after trauma: A secondary analysis of a prospective randomized trial.
Gruen DS, Brown JB, Guyette FX, Johansson PI, Stensballe J, Li SR, Leeper CM, Eastridge BJ, Nirula R, Vercruysse GA, O'Keeffe T, Joseph B, Neal MD, Sperry JL. Gruen DS, et al. Among authors: li sr. J Trauma Acute Care Surg. 2023 Nov 1;95(5):642-648. doi: 10.1097/TA.0000000000003955. Epub 2023 May 1. J Trauma Acute Care Surg. 2023. PMID: 37125811 Free PMC article. Clinical Trial.
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