Li S - Search Results

1

Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.

Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, Liu Y, Zou G, Lavillete D, Zhao Z, Wang R, Zhu L, Xiao G, Lan K, Li H, Xu K. Xiong R, et al. Among authors: li s, li h. Protein Cell. 2020 Oct;11(10):723-739. doi: 10.1007/s13238-020-00768-w. Epub 2020 Aug 4. Protein Cell. 2020. PMID: 32754890 Free PMC article.

2

Identification of inhibitors against p90 ribosomal S6 kinase 2 (RSK2) through structure-based virtual screening with the inhibitor-constrained refined homology model.

Li S, Zhou Y, Lu W, Zhong Y, Song W, Liu K, Huang J, Zhao Z, Xu Y, Liu X, Li H. Li S, et al. Among authors: li h. J Chem Inf Model. 2011 Nov 28;51(11):2939-47. doi: 10.1021/ci2002445. Epub 2011 Oct 21. J Chem Inf Model. 2011. PMID: 21995341

3

Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach.

Zhang S, Shan L, Li Q, Wang X, Li S, Zhang Y, Fu J, Liu X, Li H, Zhang W. Zhang S, et al. Among authors: li s, li h, li q. Evid Based Complement Alternat Med. 2014;2014:512081. doi: 10.1155/2014/512081. Epub 2014 Nov 30. Evid Based Complement Alternat Med. 2014. PMID: 25525446 Free PMC article. Review.

4

Design, synthesis, X-ray crystallographic analysis, and biological evaluation of thiazole derivatives as potent and selective inhibitors of human dihydroorotate dehydrogenase.

Zhu J, Han L, Diao Y, Ren X, Xu M, Xu L, Li S, Li Q, Dong D, Huang J, Liu X, Zhao Z, Wang R, Zhu L, Xu Y, Qian X, Li H. Zhu J, et al. Among authors: li s, li h, li q. J Med Chem. 2015 Feb 12;58(3):1123-39. doi: 10.1021/jm501127s. Epub 2015 Jan 26. J Med Chem. 2015. PMID: 25580811

5

Rational Design of Benzylidenehydrazinyl-Substituted Thiazole Derivatives as Potent Inhibitors of Human Dihydroorotate Dehydrogenase with in Vivo Anti-arthritic Activity.

Li S, Luan G, Ren X, Song W, Xu L, Xu M, Zhu J, Dong D, Diao Y, Liu X, Zhu L, Wang R, Zhao Z, Xu Y, Li H. Li S, et al. Among authors: li h. Sci Rep. 2015 Oct 7;5:14836. doi: 10.1038/srep14836. Sci Rep. 2015. PMID: 26443076 Free PMC article.

6

A Rapid Python-Based Methodology for Target-Focused Combinatorial Library Design.

Li S, Song Y, Liu X, Li H. Li S, et al. Among authors: li h. Comb Chem High Throughput Screen. 2016;19(1):25-35. doi: 10.2174/1386207318666151102094055. Comb Chem High Throughput Screen. 2016. PMID: 26522993

7

Are Topological Properties of Drug Targets Based on Protein-Protein Interaction Network Ready to Predict Potential Drug Targets?

Li S, Yu X, Zou C, Gong J, Liu X, Li H. Li S, et al. Among authors: li h. Comb Chem High Throughput Screen. 2016;19(2):109-20. doi: 10.2174/1386207319666151110122145. Comb Chem High Throughput Screen. 2016. PMID: 26552443

8

Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes.

Li S, Xu H, Cui S, Wu F, Zhang Y, Su M, Gong Y, Qiu S, Jiao Q, Qin C, Shan J, Zhang M, Wang J, Yin Q, Xu M, Liu X, Wang R, Zhu L, Li J, Xu Y, Jiang H, Zhao Z, Li J, Li H. Li S, et al. Among authors: li j, li h. J Med Chem. 2016 Jul 28;59(14):6772-90. doi: 10.1021/acs.jmedchem.6b00505. Epub 2016 Jul 19. J Med Chem. 2016. PMID: 27396490

9

PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database.

Wang X, Shen Y, Wang S, Li S, Zhang W, Liu X, Lai L, Pei J, Li H. Wang X, et al. Among authors: li s, li h. Nucleic Acids Res. 2017 Jul 3;45(W1):W356-W360. doi: 10.1093/nar/gkx374. Nucleic Acids Res. 2017. PMID: 28472422 Free PMC article.

10

Statistical Analysis, Investigation, and Prediction of the Water Positions in the Binding Sites of Proteins.

Xiao W, He Z, Sun M, Li S, Li H. Xiao W, et al. Among authors: li s, li h. J Chem Inf Model. 2017 Jul 24;57(7):1517-1528. doi: 10.1021/acs.jcim.6b00620. Epub 2017 Jun 27. J Chem Inf Model. 2017. PMID: 28605584

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