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Organoid Cultures as Preclinical Models of Non-Small Cell Lung Cancer.
Shi R, Radulovich N, Ng C, Liu N, Notsuda H, Cabanero M, Martins-Filho SN, Raghavan V, Li Q, Mer AS, Rosen JC, Li M, Wang YH, Tamblyn L, Pham NA, Haibe-Kains B, Liu G, Moghal N, Tsao MS. Shi R, et al. Among authors: li m, li q. Clin Cancer Res. 2020 Mar 1;26(5):1162-1174. doi: 10.1158/1078-0432.CCR-19-1376. Epub 2019 Nov 6. Clin Cancer Res. 2020. PMID: 31694835
Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non-Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion.
Hao J, Zeltz C, Pintilie M, Li Q, Sakashita S, Wang T, Cabanero M, Martins-Filho SN, Wang DY, Pasko E, Venkat K, Joseph J, Raghavan V, Zhu CQ, Wang YH, Moghal N, Tsao MS, Navab R. Hao J, et al. Among authors: li q. Neoplasia. 2019 May;21(5):482-493. doi: 10.1016/j.neo.2019.03.009. Epub 2019 Apr 9. Neoplasia. 2019. PMID: 30978569 Free PMC article.
EGFR-mutated lung adenocarcinomas from patients who progressed on EGFR-inhibitors show high engraftment rates in xenograft models.
Martins-Filho SN, Weiss J, Pham NA, Li Q, Cabanero M, Fares A, Stewart EL, Shi R, Patel D, Pal P, McConnell J, Bradbury PA, Sacher AG, Leighl NB, Grindlay A, Allison F, Li M, Yasufuku K, Shepherd FA, Moghal N, Tsao MS, Liu G. Martins-Filho SN, et al. Among authors: li m, li q. Lung Cancer. 2020 Jul;145:144-151. doi: 10.1016/j.lungcan.2020.03.022. Epub 2020 May 11. Lung Cancer. 2020. PMID: 32447118
BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer.
Shi R, Filho SNM, Li M, Fares A, Weiss J, Pham NA, Ludkovski O, Raghavan V, Li Q, Ravi D, Cabanero M, Moghal N, Leighl NB, Bradbury P, Sacher A, Shepherd FA, Yasufuku K, Tsao MS, Liu G. Shi R, et al. Among authors: li m, li q. Lung Cancer. 2020 Aug;146:78-85. doi: 10.1016/j.lungcan.2020.05.018. Epub 2020 May 21. Lung Cancer. 2020. PMID: 32521388
Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers.
Pham NA, Radulovich N, Ibrahimov E, Martins-Filho SN, Li Q, Pintilie M, Weiss J, Raghavan V, Cabanero M, Denroche RE, Wilson JM, Metran-Nascente C, Borgida A, Hutchinson S, Dodd A, Begora M, Chadwick D, Serra S, Knox JJ, Gallinger S, Hedley DW, Muthuswamy L, Tsao MS. Pham NA, et al. Among authors: li q. Sci Rep. 2021 May 19;11(1):10619. doi: 10.1038/s41598-021-90049-1. Sci Rep. 2021. PMID: 34011980 Free PMC article.
Lung Cancer Driven by BRAFG469V Mutation Is Targetable by EGFR Kinase Inhibitors.
Huo KG, Notsuda H, Fang Z, Liu NF, Gebregiworgis T, Li Q, Pham NA, Li M, Liu N, Shepherd FA, Marshall CB, Ikura M, Moghal N, Tsao MS. Huo KG, et al. Among authors: li m, li q. J Thorac Oncol. 2022 Feb;17(2):277-288. doi: 10.1016/j.jtho.2021.09.008. Epub 2021 Oct 12. J Thorac Oncol. 2022. PMID: 34648945 Free article.
Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes.
Mirhadi S, Tam S, Li Q, Moghal N, Pham NA, Tong J, Golbourn BJ, Krieger JR, Taylor P, Li M, Weiss J, Martins-Filho SN, Raghavan V, Mamatjan Y, Khan AA, Cabanero M, Sakashita S, Huo K, Agnihotri S, Ishizawa K, Waddell TK, Zadeh G, Yasufuku K, Liu G, Shepherd FA, Moran MF, Tsao MS. Mirhadi S, et al. Among authors: li m, li q. Nat Commun. 2022 Apr 5;13(1):1811. doi: 10.1038/s41467-022-29444-9. Nat Commun. 2022. PMID: 35383171 Free PMC article.
Single-Cell Analysis Reveals Transcriptomic Features of Drug-Tolerant Persisters and Stromal Adaptation in a Patient-Derived EGFR-Mutated Lung Adenocarcinoma Xenograft Model.
Moghal N, Li Q, Stewart EL, Navab R, Mikubo M, D'Arcangelo E, Martins-Filho SN, Raghavan V, Pham NA, Li M, Shepherd FA, Liu G, Tsao MS. Moghal N, et al. Among authors: li m, li q. J Thorac Oncol. 2023 Apr;18(4):499-515. doi: 10.1016/j.jtho.2022.12.003. Epub 2022 Dec 16. J Thorac Oncol. 2023. PMID: 36535627 Free article.
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