Li J - Search Results

1

p300/CBP inhibitor A-485 alleviates acute liver injury by regulating macrophage activation and polarization.

Peng J, Li J, Huang J, Xu P, Huang H, Liu Y, Yu L, Yang Y, Zhou B, Jiang H, Chen K, Dang Y, Zhang Y, Luo C, Li G. Peng J, et al. Among authors: li j, li g. Theranostics. 2019 Oct 22;9(26):8344-8361. doi: 10.7150/thno.30707. eCollection 2019. Theranostics. 2019. PMID: 31754401 Free PMC article.

2

Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors.

Lin T, Li J, Liu L, Li Y, Jiang H, Chen K, Xu P, Luo C, Zhou B. Lin T, et al. Among authors: li y, li j. Eur J Med Chem. 2021 Apr 5;215:113281. doi: 10.1016/j.ejmech.2021.113281. Epub 2021 Feb 11. Eur J Med Chem. 2021. PMID: 33611192

3

Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury.

Liu Y, Li J, Liao L, Huang H, Fan S, Fu R, Huang J, Shi C, Yu L, Chen KX, Zhang YY, Luo C, Li GM. Liu Y, et al. Among authors: li j, li gm. Clin Sci (Lond). 2021 Apr 16;135(7):925-941. doi: 10.1042/CS20201111. Clin Sci (Lond). 2021. PMID: 33786590

4

P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib.

Zhou XR, Li X, Liao LP, Han J, Huang J, Li JC, Tao HR, Fan SJ, Chen ZF, Li Q, Chen SJ, Ding H, Yang YX, Zhou B, Jiang HL, Chen KX, Zhang YY, Huang CX, Luo C. Zhou XR, et al. Among authors: li x, li q, li jc. Acta Pharmacol Sin. 2022 Feb;43(2):457-469. doi: 10.1038/s41401-021-00643-2. Epub 2021 Apr 13. Acta Pharmacol Sin. 2022. PMID: 33850273 Free PMC article.

5

Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1).

Liu L, Zhu R, Li J, Pei Y, Wang S, Xu P, Wang M, Wen Y, Zhang H, Du D, Ding H, Jiang H, Chen K, Zhou B, Yu L, Luo C. Liu L, et al. Among authors: li j. J Med Chem. 2022 Feb 10;65(3):2174-2190. doi: 10.1021/acs.jmedchem.1c01686. Epub 2022 Jan 28. J Med Chem. 2022. PMID: 35089030

6

Selective bromodomain and extra-terminal bromodomain inhibitor inactivates macrophages and hepatic stellate cells to inhibit liver inflammation and fibrosis.

Fu R, Zu SJ, Liu YJ, Li JC, Dang WZ, Liao LP, Liu LP, Chen PY, Huang HM, Wu KH, Zhou B, Pan Q, Luo C, Zhang YY, Li GM. Fu R, et al. Bioengineered. 2022 Apr;13(4):10914-10930. doi: 10.1080/21655979.2022.2066756. Bioengineered. 2022. PMID: 35499161 Free PMC article.

7

Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer.

Li J, Liu T, Song Y, Wang M, Liu L, Zhu H, Li Q, Lin J, Jiang H, Chen K, Zhao K, Wang M, Zhou H, Lin H, Luo C. Li J, et al. Among authors: li q. J Med Chem. 2022 Aug 25;65(16):11034-11057. doi: 10.1021/acs.jmedchem.2c00257. Epub 2022 Aug 4. J Med Chem. 2022. PMID: 35925880

8

A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1β and IL-6.

Liao L, Dang W, Lin T, Yu J, Liu T, Li W, Xiao S, Feng L, Huang J, Fu R, Li J, Liu L, Wang M, Tao H, Jiang H, Chen K, Diao X, Zhou B, Shen X, Luo C. Liao L, et al. Among authors: li j, li w. Acta Pharm Sin B. 2022 Nov;12(11):4180-4192. doi: 10.1016/j.apsb.2022.05.012. Epub 2022 May 14. Acta Pharm Sin B. 2022. PMID: 36386479 Free PMC article.

9

Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase.

Zheng M, Luan S, Gao S, Cheng L, Hao B, Li J, Chen Y, Hou X, Chen L, Li H. Zheng M, et al. Among authors: li j, li h. Oncotarget. 2017 Jun 13;8(24):39143-39153. doi: 10.18632/oncotarget.16609. Oncotarget. 2017. PMID: 28388576 Free PMC article.

10

Hydroxysafflor Yellow A Alleviates Acute Myocardial Ischemia/Reperfusion Injury in Mice by Inhibiting Ferroptosis via the Activation of the HIF-1α/SLC7A11/GPX4 Signaling Pathway.

Ge C, Peng Y, Li J, Wang L, Zhu X, Wang N, Yang D, Zhou X, Chang D. Ge C, et al. Among authors: li j. Nutrients. 2023 Jul 31;15(15):3411. doi: 10.3390/nu15153411. Nutrients. 2023. PMID: 37571350 Free PMC article.

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