Li D - Search Results

1

Clinical pharmacology strategies to accelerate the development of polatuzumab vedotin and summary of key findings.

Liao MZ, Lu D, Lu T, Gibiansky L, Deng R, Samineni D, Dere R, Lin A, Hirata J, Shen BQ, Zhang D, Li D, Li C, Miles D. Liao MZ, et al. Among authors: li c, li d. Adv Drug Deliv Rev. 2024 Apr;207:115193. doi: 10.1016/j.addr.2024.115193. Epub 2024 Feb 3. Adv Drug Deliv Rev. 2024. PMID: 38311111 Free article. Review.

2

Evaluation and use of an anti-cynomolgus monkey CD79b surrogate antibody-drug conjugate to enable clinical development of polatuzumab vedotin.

Li D, Lee D, Dere RC, Zheng B, Yu SF, Fuh FK, Kozak KR, Chung S, Bumbaca Yadav D, Nazzal D, Danilenko D, Go MAT, Williams M, Polson AG, Poon KA, Prabhu S. Li D, et al. Br J Pharmacol. 2019 Oct;176(19):3805-3818. doi: 10.1111/bph.14784. Epub 2019 Aug 24. Br J Pharmacol. 2019. PMID: 31270798 Free PMC article.

3

Antibody delivery of drugs and radionuclides: factors influencing clinical pharmacology.

Prabhu S, Boswell CA, Leipold D, Khawli LA, Li D, Lu D, Theil FP, Joshi A, Lum BL. Prabhu S, et al. Among authors: li d. Ther Deliv. 2011 Jun;2(6):769-91. doi: 10.4155/tde.11.41. Ther Deliv. 2011. PMID: 22822508 Review.

4

Prediction of Human Pharmacokinetics of Antibody-Drug Conjugates From Nonclinical Data.

Li C, Zhang C, Deng R, Leipold D, Li D, Latifi B, Gao Y, Zhang C, Li Z, Miles D, Chen SC, Samineni D, Wang B, Agarwal P, Lu D, Prabhu S, Girish S, Kamath AV. Li C, et al. Among authors: li d, li z. Clin Transl Sci. 2019 Sep;12(5):534-544. doi: 10.1111/cts.12649. Epub 2019 Jun 11. Clin Transl Sci. 2019. PMID: 31115997 Free PMC article.

5

Semi-mechanistic Multiple-Analyte Pharmacokinetic Model for an Antibody-Drug-Conjugate in Cynomolgus Monkeys.

Lu D, Jin JY, Girish S, Agarwal P, Li D, Prabhu S, Dere RC, Saad OM, Nazzal D, Koppada N, Ramanujan S, Ng CM. Lu D, et al. Among authors: li d. Pharm Res. 2015 Jun;32(6):1907-19. doi: 10.1007/s11095-014-1585-y. Epub 2014 Dec 3. Pharm Res. 2015. PMID: 25467958 Free PMC article.

6

DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma.

Li D, Poon KA, Yu SF, Dere R, Go M, Lau J, Zheng B, Elkins K, Danilenko D, Kozak KR, Chan P, Chuh J, Shi X, Nazzal D, Fuh F, McBride J, Ramakrishnan V, de Tute R, Rawstron A, Jack AS, Deng R, Chu YW, Dornan D, Williams M, Ho W, Ebens A, Prabhu S, Polson AG. Li D, et al. Mol Cancer Ther. 2013 Jul;12(7):1255-65. doi: 10.1158/1535-7163.MCT-12-1173. Epub 2013 Apr 18. Mol Cancer Ther. 2013. PMID: 23598530

7

Anti-CD22 and anti-CD79b antibody-drug conjugates preferentially target proliferating B cells.

Fuh FK, Looney C, Li D, Poon KA, Dere RC, Danilenko DM, McBride J, Reed C, Chung S, Zheng B, Mathews WR, Polson A, Prabhu S, Williams M. Fuh FK, et al. Among authors: li d. Br J Pharmacol. 2017 Apr;174(8):628-640. doi: 10.1111/bph.13697. Epub 2017 Mar 6. Br J Pharmacol. 2017. PMID: 28009435 Free PMC article.

8

Preclinical and translational pharmacokinetics of a novel THIOMAB™ antibody-antibiotic conjugate against Staphylococcus aureus.

Deng R, Zhou C, Li D, Cai H, Sukumaran S, Carrasco-Triguero M, Saad O, Nazzal D, Lowe C, Ramanujan S, Kamath AV. Deng R, et al. Among authors: li d. MAbs. 2019 Aug/Sep;11(6):1162-1174. doi: 10.1080/19420862.2019.1627152. Epub 2019 Jun 20. MAbs. 2019. PMID: 31219754 Free PMC article.

9

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.

Shen BQ, Xu K, Liu L, Raab H, Bhakta S, Kenrick M, Parsons-Reponte KL, Tien J, Yu SF, Mai E, Li D, Tibbitts J, Baudys J, Saad OM, Scales SJ, McDonald PJ, Hass PE, Eigenbrot C, Nguyen T, Solis WA, Fuji RN, Flagella KM, Patel D, Spencer SD, Khawli LA, Ebens A, Wong WL, Vandlen R, Kaur S, Sliwkowski MX, Scheller RH, Polakis P, Junutula JR. Shen BQ, et al. Among authors: li d. Nat Biotechnol. 2012 Jan 22;30(2):184-9. doi: 10.1038/nbt.2108. Nat Biotechnol. 2012. PMID: 22267010

10

Method development of a novel PK assay for antibody-conjugated drug measurement of ADCs using peptide-linker drug analyte.

Hyung SJ, Li D, Koppada N, Kaur S, Saad OM. Hyung SJ, et al. Among authors: li d. Anal Bioanal Chem. 2019 May;411(12):2587-2596. doi: 10.1007/s00216-019-01701-9. Epub 2019 Mar 4. Anal Bioanal Chem. 2019. PMID: 30828756

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