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Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: A triple blinded, placebo controlled, randomized phase I/II safety and feasibility study.
Fernández O, Izquierdo G, Fernández V, Leyva L, Reyes V, Guerrero M, León A, Arnaiz C, Navarro G, Páramo MD, Cuesta A, Soria B, Hmadcha A, Pozo D, Fernandez-Montesinos R, Leal M, Ochotorena I, Gálvez P, Geniz MA, Barón FJ, Mata R, Medina C, Caparrós-Escudero C, Cardesa A, Cuende N; Research Group Study EudraCT 2008-004015-35. Fernández O, et al. Among authors: leyva l. PLoS One. 2018 May 16;13(5):e0195891. doi: 10.1371/journal.pone.0195891. eCollection 2018. PLoS One. 2018. PMID: 29768414 Free PMC article. Clinical Trial.
Mesenchymal Stem Cells From Adipose Tissue Do not Improve Functional Recovery After Ischemic Stroke in Hypertensive Rats.
Diekhorst L, Gómez-de Frutos MC, Laso-García F, Otero-Ortega L, Fuentes B, Jolkkonen J, Detante O, Moisan A, Leyva L, Martínez-Arroyo A, Díez-Tejedor E, Gutiérrez-Fernández M; RESSTORE Consortium. Diekhorst L, et al. Among authors: leyva l. Stroke. 2020 Jan;51(1):342-346. doi: 10.1161/STROKEAHA.119.027133. Epub 2019 Nov 7. Stroke. 2020. PMID: 31694504 Free article.
Gene therapy with mesenchymal stem cells expressing IFN-ß ameliorates neuroinflammation in experimental models of multiple sclerosis.
Marin-Bañasco C, Benabdellah K, Melero-Jerez C, Oliver B, Pinto-Medel MJ, Hurtado-Guerrero I, de Castro F, Clemente D, Fernández O, Martin F, Leyva L, Suardíaz M. Marin-Bañasco C, et al. Among authors: leyva l. Br J Pharmacol. 2017 Feb;174(3):238-253. doi: 10.1111/bph.13674. Epub 2017 Jan 12. Br J Pharmacol. 2017. PMID: 27882538 Free PMC article.
Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß.
Hurtado-Guerrero I, Pinto-Medel MJ, Urbaneja P, Rodriguez-Bada JL, León A, Guerrero M, Fernández Ó, Leyva L, Oliver-Martos B. Hurtado-Guerrero I, et al. Among authors: leyva l. PLoS One. 2017 Jan 19;12(1):e0170031. doi: 10.1371/journal.pone.0170031. eCollection 2017. PLoS One. 2017. PMID: 28103257 Free PMC article.
HLA class II and response to interferon-beta in multiple sclerosis.
Fernández O, Fernández V, Mayorga C, Guerrero M, León A, Tamayo JA, Alonso A, Romero F, Leyva L, Alonso A, Luque G, de Ramón E. Fernández O, et al. Among authors: leyva l. Acta Neurol Scand. 2005 Dec;112(6):391-4. doi: 10.1111/j.1600-0404.2005.00415.x. Acta Neurol Scand. 2005. PMID: 16281922
83 results