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Loss of mouse Stmn2 function causes motor neuropathy.
Neuron. 2022 May 18;110(10):1671-1688.e6. doi: 10.1016/j.neuron.2022.02.011. Epub 2022 Mar 15.
Neuron. 2022.
PMID: 35294901
Free PMC article.
Targeting the Mitochondrial Protein VDAC1 as a Potential Therapeutic Strategy in ALS.
Shteinfer-Kuzmine A, Argueti-Ostrovsky S, Leyton-Jaimes MF, Anand U, Abu-Hamad S, Zalk R, Shoshan-Barmatz V, Israelson A.
Shteinfer-Kuzmine A, et al. Among authors: leyton jaimes mf.
Int J Mol Sci. 2022 Sep 1;23(17):9946. doi: 10.3390/ijms23179946.
Int J Mol Sci. 2022.
PMID: 36077343
Free PMC article.
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Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS.
Leyton-Jaimes MF, Ivert P, Hoeber J, Han Y, Feiler A, Zhou C, Pankratova S, Shoshan-Barmatz V, Israelson A, Kozlova EN.
Leyton-Jaimes MF, et al.
Sci Rep. 2020 Nov 26;10(1):20675. doi: 10.1038/s41598-020-77578-x.
Sci Rep. 2020.
PMID: 33244084
Free PMC article.
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Misfolded SOD1 Accumulation and Mitochondrial Association Contribute to the Selective Vulnerability of Motor Neurons in Familial ALS: Correlation to Human Disease.
Abu-Hamad S, Kahn J, Leyton-Jaimes MF, Rosenblatt J, Israelson A.
Abu-Hamad S, et al. Among authors: leyton jaimes mf.
ACS Chem Neurosci. 2017 Oct 18;8(10):2225-2234. doi: 10.1021/acschemneuro.7b00140. Epub 2017 Jul 31.
ACS Chem Neurosci. 2017.
PMID: 28715630
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AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS.
Leyton-Jaimes MF, Kahn J, Israelson A.
Leyton-Jaimes MF, et al.
Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14755-14760. doi: 10.1073/pnas.1904665116. Epub 2019 Jul 1.
Proc Natl Acad Sci U S A. 2019.
PMID: 31262807
Free PMC article.
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Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.
Leyton-Jaimes MF, Benaim C, Abu-Hamad S, Kahn J, Guetta A, Bucala R, Israelson A.
Leyton-Jaimes MF, et al.
Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10198-203. doi: 10.1073/pnas.1604600113. Epub 2016 Aug 22.
Proc Natl Acad Sci U S A. 2016.
PMID: 27551074
Free PMC article.
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Macrophage migration inhibitory factor: A multifaceted cytokine implicated in multiple neurological diseases.
Leyton-Jaimes MF, Kahn J, Israelson A.
Leyton-Jaimes MF, et al.
Exp Neurol. 2018 Mar;301(Pt B):83-91. doi: 10.1016/j.expneurol.2017.06.021. Epub 2017 Jul 2.
Exp Neurol. 2018.
PMID: 28679106
Review.
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Loss of mouse Stmn2 function causes motor neuropathy.
San Juan IG, Nash LA, Smith KS, Leyton-Jaimes MF, Qian M, Klim JR, Limone F, Dorr AB, Couto A, Pintacuda G, Joseph BJ, Whisenant DE, Noble C, Melnik V, Potter D, Holmes A, Burberry A, Verhage M, Eggan K.
San Juan IG, et al. Among authors: leyton jaimes mf.
Neuron. 2022 Dec 7;110(23):4031. doi: 10.1016/j.neuron.2022.11.003.
Neuron. 2022.
PMID: 36480942
Free article.
No abstract available.
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