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Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells.
Meyer A, Sienes RE, Nijim W, Zanotti B, Umar S, Volin MV, Van Raemdonck K, Lewis M, Pitzalis C, Arami S, Al-Awqati M, Chang HJ, Jetanalin P, Schett G, Sweiss N, Shahrara S. Meyer A, et al. Among authors: lewis m. Ann Rheum Dis. 2023 Apr;82(4):483-495. doi: 10.1136/ard-2022-223284. Epub 2023 Jan 2. Ann Rheum Dis. 2023. PMID: 36593091 Free PMC article.
PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes.
Bottini A, Wu DJ, Ai R, Le Roux M, Bartok B, Bombardieri M, Doody KM, Zhang V, Sacchetti C, Zoccheddu M, Lonic A, Li X, Boyle DL, Hammaker D, Meng TC, Liu L, Corr M, Stanford SM, Lewis M, Wang W, Firestein GS, Khew-Goodall Y, Pitzalis C, Bottini N. Bottini A, et al. Among authors: lewis m. Ann Rheum Dis. 2019 May;78(5):600-609. doi: 10.1136/annrheumdis-2018-213799. Epub 2019 Feb 26. Ann Rheum Dis. 2019. PMID: 30808624 Free PMC article.
Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients.
Humby F, Lewis M, Ramamoorthi N, Hackney JA, Barnes MR, Bombardieri M, Setiadi AF, Kelly S, Bene F, DiCicco M, Riahi S, Rocher V, Ng N, Lazarou I, Hands R, van der Heijde D, Landewé RBM, van der Helm-van Mil A, Cauli A, McInnes I, Buckley CD, Choy EH, Taylor PC, Townsend MJ, Pitzalis C. Humby F, et al. Among authors: lewis m. Ann Rheum Dis. 2019 Jun;78(6):761-772. doi: 10.1136/annrheumdis-2018-214539. Epub 2019 Mar 16. Ann Rheum Dis. 2019. PMID: 30878974 Free PMC article.
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC).
Lliso-Ribera G, Humby F, Lewis M, Nerviani A, Mauro D, Rivellese F, Kelly S, Hands R, Bene F, Ramamoorthi N, Hackney JA, Cauli A, Choy EH, Filer A, Taylor PC, McInnes I, Townsend MJ, Pitzalis C. Lliso-Ribera G, et al. Among authors: lewis m. Ann Rheum Dis. 2019 Dec;78(12):1642-1652. doi: 10.1136/annrheumdis-2019-215751. Epub 2019 Oct 2. Ann Rheum Dis. 2019. PMID: 31582377 Free PMC article.
Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring.
Pucino V, Certo M, Bulusu V, Cucchi D, Goldmann K, Pontarini E, Haas R, Smith J, Headland SE, Blighe K, Ruscica M, Humby F, Lewis MJ, Kamphorst JJ, Bombardieri M, Pitzalis C, Mauro C. Pucino V, et al. Among authors: lewis mj. Cell Metab. 2019 Dec 3;30(6):1055-1074.e8. doi: 10.1016/j.cmet.2019.10.004. Epub 2019 Nov 7. Cell Metab. 2019. PMID: 31708446 Free PMC article.
M3C: Monte Carlo reference-based consensus clustering.
John CR, Watson D, Russ D, Goldmann K, Ehrenstein M, Pitzalis C, Lewis M, Barnes M. John CR, et al. Among authors: lewis m. Sci Rep. 2020 Feb 4;10(1):1816. doi: 10.1038/s41598-020-58766-1. Sci Rep. 2020. PMID: 32020004 Free PMC article.
7,248 results