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Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression.
Ashayeripanah M, Vega-Ramos J, Fernandez-Ruiz D, Valikhani S, Lun ATL, White JT, Young LJ, Yaftiyan A, Zhan Y, Wakim L, Caminschi I, Lahoud MH, Lew AM, Shortman K, Smyth GK, Heath WR, Mintern JD, Roquilly A, Villadangos JA. Ashayeripanah M, et al. Among authors: lew am. Cell Rep. 2024 Feb 27;43(2):113754. doi: 10.1016/j.celrep.2024.113754. Epub 2024 Feb 13. Cell Rep. 2024. PMID: 38354086 Free article.
RIPK3 controls MAIT cell accumulation during development but not during infection.
Patton T, Zhao Z, Lim XY, Eddy E, Wang H, Nelson AG, Ennis B, Eckle SBG, Souter MNT, Pediongco TJ, Koay HF, Zhang JG, Djajawi TM, Louis C, Lalaoui N, Jacquelot N, Lew AM, Pellicci DG, McCluskey J, Zhan Y, Chen Z, Lawlor KE, Corbett AJ. Patton T, et al. Among authors: lew am. Cell Death Dis. 2023 Feb 11;14(2):111. doi: 10.1038/s41419-023-05619-0. Cell Death Dis. 2023. PMID: 36774342 Free PMC article.
CIS controls the functional polarization of GM-CSF-derived macrophages.
Zhang S, Rautela J, Bediaga NG, Kolesnik TB, You Y, Nie J, Dagley LF, Bedo J, Wang H, Sun L, Sutherland R, Surgenor E, Iannarella N, Allan R, Souza-Fonseca-Guimaraes F, Xie Y, Wang Q, Zhang Y, Xu Y, Nutt SL, Lew AM, Huntington ND, Nicholson SE, Chopin M, Zhan Y. Zhang S, et al. Among authors: lew am. Cell Mol Immunol. 2023 Jan;20(1):65-79. doi: 10.1038/s41423-022-00957-z. Epub 2022 Dec 5. Cell Mol Immunol. 2023. PMID: 36471114 Free PMC article.
Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasis.
Zhan Y, Zhang Y, Zhang S, Coughlan H, Baldoni PL, Jacquelot N, Cao WHJ, Preston S, Louis C, Rautela J, Pellegrini M, Wicks IP, Alexander WS, Harrison LC, Lew AM, Smyth GK, Nutt SL, Chopin M. Zhan Y, et al. Among authors: lew am. Sci Immunol. 2021 Sep 17;6(63):eabf7268. doi: 10.1126/sciimmunol.abf7268. Epub 2021 Sep 17. Sci Immunol. 2021. PMID: 34533976
BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without causing neutropenia.
Carrington EM, Louis C, Kratina T, Hancock M, Keenan CR, Iannarella N, Allan RS, Wardak AZ, Czabotar PE, Herold MJ, Schenk RL, White CA, D'Silva D, Yang Y, Wong W, Wong H, Bryant VL, Huntington ND, Rautela J, Sutherland RM, Zhan Y, Hansen J, Nhu D, Lessene G, Wicks IP, Lew AM. Carrington EM, et al. Among authors: lew am. Blood Adv. 2021 Jun 8;5(11):2550-2562. doi: 10.1182/bloodadvances.2020004139. Blood Adv. 2021. PMID: 34100903 Free PMC article.
Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT.
Zhang S, Coughlan HD, Ashayeripanah M, Seizova S, Kueh AJ, Brown DV, Cao W, Jacquelot N, D'Amico A, Lew AM, Zhan Y, Tonkin CJ, Villadangos JA, Smyth GK, Chopin M, Nutt SL. Zhang S, et al. Among authors: lew am. Sci Immunol. 2021 Apr 2;6(58):eabf4432. doi: 10.1126/sciimmunol.abf4432. Sci Immunol. 2021. PMID: 33811060
Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia.
Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, Xu Y, Wu Q, Guo X, Nie J, Lu B, Huang B, Xian H, Wang X, Wu Q, Zeng J, Chai C, Zhang M, Lin Y, Zhang L, Zhao S, Tong Y, Zeng L, Gu X, Chen ZG, Yi S, Zhang T, Delfouneso D, Zhang Y, Nutt SL, Lew AM, Lu L, Bai F, Xia H, Wen Z, Zhang Y. Wang J, et al. Among authors: lew am. Cell. 2020 Dec 23;183(7):1867-1883.e26. doi: 10.1016/j.cell.2020.10.048. Epub 2020 Nov 27. Cell. 2020. PMID: 33248023 Free article.
255 results