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A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.
Ghigo A, Murabito A, Sala V, Pisano AR, Bertolini S, Gianotti A, Caci E, Montresor A, Premchandar A, Pirozzi F, Ren K, Della Sala A, Mergiotti M, Richter W, de Poel E, Matthey M, Caldrer S, Cardone RA, Civiletti F, Costamagna A, Quinney NL, Butnarasu C, Visentin S, Ruggiero MR, Baroni S, Crich SG, Ramel D, Laffargue M, Tocchetti CG, Levi R, Conti M, Lu XY, Melotti P, Sorio C, De Rose V, Facchinetti F, Fanelli V, Wenzel D, Fleischmann BK, Mall MA, Beekman J, Laudanna C, Gentzsch M, Lukacs GL, Pedemonte N, Hirsch E. Ghigo A, et al. Among authors: levi r. Sci Transl Med. 2022 Mar 30;14(638):eabl6328. doi: 10.1126/scitranslmed.abl6328. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353541 Free PMC article.
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ.
Perino A, Ghigo A, Ferrero E, Morello F, Santulli G, Baillie GS, Damilano F, Dunlop AJ, Pawson C, Walser R, Levi R, Altruda F, Silengo L, Langeberg LK, Neubauer G, Heymans S, Lembo G, Wymann MP, Wetzker R, Houslay MD, Iaccarino G, Scott JD, Hirsch E. Perino A, et al. Among authors: levi r. Mol Cell. 2011 Apr 8;42(1):84-95. doi: 10.1016/j.molcel.2011.01.030. Mol Cell. 2011. PMID: 21474070 Free PMC article.
Homing of annexin-labeled stem cells to apoptotic cells.
Gerasimou A, Ramella R, Brero A, Boero O, Sheiban I, Levi R, Gallo MP. Gerasimou A, et al. Among authors: levi r. Cell Mol Biol Lett. 2009;14(1):100-12. doi: 10.2478/s11658-008-0038-1. Epub 2008 Oct 6. Cell Mol Biol Lett. 2009. PMID: 18839068 Free PMC article.
STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy.
Camporeale A, Marino F, Papageorgiou A, Carai P, Fornero S, Fletcher S, Page BD, Gunning P, Forni M, Chiarle R, Morello M, Jensen O, Levi R, Heymans S, Poli V. Camporeale A, et al. Among authors: levi r. EMBO Mol Med. 2013 Apr;5(4):572-90. doi: 10.1002/emmm.201201876. Epub 2013 Mar 5. EMBO Mol Med. 2013. PMID: 23460527 Free PMC article.
536 results