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Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade.
Ishizuka JJ, Manguso RT, Cheruiyot CK, Bi K, Panda A, Iracheta-Vellve A, Miller BC, Du PP, Yates KB, Dubrot J, Buchumenski I, Comstock DE, Brown FD, Ayer A, Kohnle IC, Pope HW, Zimmer MD, Sen DR, Lane-Reticker SK, Robitschek EJ, Griffin GK, Collins NB, Long AH, Doench JG, Kozono D, Levanon EY, Haining WN. Ishizuka JJ, et al. Among authors: levanon ey. Nature. 2019 Jan;565(7737):43-48. doi: 10.1038/s41586-018-0768-9. Epub 2018 Dec 17. Nature. 2019. PMID: 30559380 Free PMC article.
Dynamic hyper-editing underlies temperature adaptation in Drosophila.
Buchumenski I, Bartok O, Ashwal-Fluss R, Pandey V, Porath HT, Levanon EY, Kadener S. Buchumenski I, et al. Among authors: levanon ey. PLoS Genet. 2017 Jul 26;13(7):e1006931. doi: 10.1371/journal.pgen.1006931. eCollection 2017 Jul. PLoS Genet. 2017. PMID: 28746393 Free PMC article.
RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure.
Solomon O, Di Segni A, Cesarkas K, Porath HT, Marcu-Malina V, Mizrahi O, Stern-Ginossar N, Kol N, Farage-Barhom S, Glick-Saar E, Lerenthal Y, Levanon EY, Amariglio N, Unger R, Goldstein I, Eyal E, Rechavi G. Solomon O, et al. Among authors: levanon ey. Nat Commun. 2017 Nov 13;8(1):1440. doi: 10.1038/s41467-017-01458-8. Nat Commun. 2017. PMID: 29129909 Free PMC article.
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells.
Gannon HS, Zou T, Kiessling MK, Gao GF, Cai D, Choi PS, Ivan AP, Buchumenski I, Berger AC, Goldstein JT, Cherniack AD, Vazquez F, Tsherniak A, Levanon EY, Hahn WC, Meyerson M. Gannon HS, et al. Among authors: levanon ey. Nat Commun. 2018 Dec 21;9(1):5450. doi: 10.1038/s41467-018-07824-4. Nat Commun. 2018. PMID: 30575730 Free PMC article.
111 results