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Cancer-associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2-IGF1R and Hippo-YAP1 signaling pathways.
Zhang J, Chen B, Li H, Wang Y, Liu X, Wong KY, Chan WN, Chan AK, Cheung AH, Leung KT, Dong Y, Pan Y, Ke H, Liang L, Zhou Z, Xiao J, Wong CC, Wu WK, Cheng AS, Ma BB, Yu J, Lo KW, Kang W; Ka Fai To. Zhang J, et al. Among authors: leung kt. J Pathol. 2023 Feb;259(2):205-219. doi: 10.1002/path.6033. Epub 2022 Dec 17. J Pathol. 2023. PMID: 36373776
CD9 blockade suppresses disease progression of high-risk pediatric B-cell precursor acute lymphoblastic leukemia and enhances chemosensitivity.
Leung KT, Zhang C, Chan KYY, Li K, Cheung JTK, Ng MHL, Zhang XB, Sit T, Lee WYW, Kang W, To KF, Yu JWS, Man TKF, Wang H, Tsang KS, Cheng FWT, Lam GKS, Chow TW, Leung AWK, Leung TF, Yuen PMP, Ng PC, Li CK. Leung KT, et al. Among authors: leung awk, leung tf. Leukemia. 2020 Mar;34(3):709-720. doi: 10.1038/s41375-019-0593-7. Epub 2019 Oct 17. Leukemia. 2020. PMID: 31624373
FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
Zhang J, Wong CC, Leung KT, Wu F, Zhou Y, Tong JHM, Chan RCK, Li H, Wang Y, Yan H, Liu L, Wu WKK, Chan MWY, Cheng ASL, Yu J, Wong N, Lo KW, To KF, Kang W. Zhang J, et al. Among authors: leung kt. Oncogene. 2020 Oct;39(43):6647-6663. doi: 10.1038/s41388-020-01458-x. Epub 2020 Sep 15. Oncogene. 2020. PMID: 32934314 Free PMC article.
R4 RGS proteins suppress engraftment of human hematopoietic stem/progenitor cells by modulating SDF-1/CXCR4 signaling.
Chan KYY, Zhang C, Wong YTS, Zhang XB, Wang CC, Ng WH, Fok SP, Tang PMK, Kang W, Feng B, Poon ENY, Lee KY, Lee CK, Chen C, Leung TY, Ng MHL, To KF, Wang H, Lam HS, Ng PC, Yuen PMP, Li K, Leung AWK, Li CK, Leung KT. Chan KYY, et al. Among authors: leung awk, leung ty, leung kt. Blood Adv. 2021 Nov 9;5(21):4380-4392. doi: 10.1182/bloodadvances.2020003307. Blood Adv. 2021. PMID: 34500454 Free PMC article.
STK3 promotes gastric carcinogenesis by activating Ras-MAPK mediated cell cycle progression and serves as an independent prognostic biomarker.
Chen B, Chan WN, Mui CW, Liu X, Zhang J, Wang Y, Cheung AHK, Chan AKY, Chan RCK, Leung KT, Dong Y, Pan Y, Ke H, Liang L, Zhou Z, Wong CC, Wu WKK, Cheng ASL, Yu J, Lo KW, To KF, Kang W. Chen B, et al. Among authors: leung kt. Mol Cancer. 2021 Nov 12;20(1):147. doi: 10.1186/s12943-021-01451-2. Mol Cancer. 2021. PMID: 34772410 Free PMC article. No abstract available.
235 results