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Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy.
Rehman SK, Haynes J, Collignon E, Brown KR, Wang Y, Nixon AML, Bruce JP, Wintersinger JA, Singh Mer A, Lo EBL, Leung C, Lima-Fernandes E, Pedley NM, Soares F, McGibbon S, He HH, Pollet A, Pugh TJ, Haibe-Kains B, Morris Q, Ramalho-Santos M, Goyal S, Moffat J, O'Brien CA. Rehman SK, et al. Among authors: leung c. Cell. 2021 Jan 7;184(1):226-242.e21. doi: 10.1016/j.cell.2020.11.018. Cell. 2021. PMID: 33417860 Free PMC article.
Self-renewal as a therapeutic target in human colorectal cancer.
Kreso A, van Galen P, Pedley NM, Lima-Fernandes E, Frelin C, Davis T, Cao L, Baiazitov R, Du W, Sydorenko N, Moon YC, Gibson L, Wang Y, Leung C, Iscove NN, Arrowsmith CH, Szentgyorgyi E, Gallinger S, Dick JE, O'Brien CA. Kreso A, et al. Among authors: leung c. Nat Med. 2014 Jan;20(1):29-36. doi: 10.1038/nm.3418. Epub 2013 Dec 1. Nat Med. 2014. PMID: 24292392
Administration of Hypoxia-Activated Prodrug Evofosfamide after Conventional Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Preclinical Models of Colorectal Cancer.
Haynes J, McKee TD, Haller A, Wang Y, Leung C, Gendoo DMA, Lima-Fernandes E, Kreso A, Wolman R, Szentgyorgyi E, Vines DC, Haibe-Kains B, Wouters BG, Metser U, Jaffray DA, Smith M, O'Brien CA. Haynes J, et al. Among authors: leung c. Clin Cancer Res. 2018 May 1;24(9):2116-2127. doi: 10.1158/1078-0432.CCR-17-1715. Epub 2018 Feb 23. Clin Cancer Res. 2018. PMID: 29476017
Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells.
Lima-Fernandes E, Murison A, da Silva Medina T, Wang Y, Ma A, Leung C, Luciani GM, Haynes J, Pollett A, Zeller C, Duan S, Kreso A, Barsyte-Lovejoy D, Wouters BG, Jin J, Carvalho DD, Lupien M, Arrowsmith CH, O'Brien CA. Lima-Fernandes E, et al. Among authors: leung c. Nat Commun. 2019 Mar 29;10(1):1436. doi: 10.1038/s41467-019-09309-4. Nat Commun. 2019. PMID: 30926792 Free PMC article.
A surge in food insecurity during the COVID-19 pandemic in a cohort in Mexico City.
Bautista-Arredondo LF, Muñoz-Rocha TV, Figueroa JL, Téllez-Rojo MM, Torres-Olascoaga LA, Cantoral A, Arboleda-Merino L, Leung C, Peterson KE, Lamadrid-Figueroa H. Bautista-Arredondo LF, et al. Among authors: leung c. PLoS One. 2024 May 10;19(5):e0297694. doi: 10.1371/journal.pone.0297694. eCollection 2024. PLoS One. 2024. PMID: 38728255 Free PMC article.
Prevalence of SARS-CoV-2 in newborns born to SARS-CoV-2-positive mothers at 2 weeks of life.
Jan S, Katz R, Fagan D, Santos T, Beachy JC, Steinway C, Chen J, Tsouristakis A, Mancenido B, Leung C, Moore E, Wilson E, Lin L, Harte M, Katzow M, Rubin LG. Jan S, et al. Among authors: leung c. Front Pediatr. 2024 Apr 25;12:1381104. doi: 10.3389/fped.2024.1381104. eCollection 2024. Front Pediatr. 2024. PMID: 38725986 Free PMC article.
2,903 results