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Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study.
Trépo E, Caruso S, Yang J, Imbeaud S, Couchy G, Bayard Q, Letouzé E, Ganne-Carrié N, Moreno C, Oussalah A, Féray C, Blanc JF, Clément B, Hillon P, Boursier J, Paradis V, Calderaro J, Gnemmi V, Nault JC, Guéant JL, Devière J, Archambeaud I, Vitellius C, Turlin B, Bronowicki JP, Gustot T, Sutton A; GENTHEP Consortium; Ziol M, Nahon P, Zucman-Rossi J. Trépo E, et al. Among authors: letouze e. Lancet Oncol. 2022 Jan;23(1):161-171. doi: 10.1016/S1470-2045(21)00603-3. Epub 2021 Dec 11. Lancet Oncol. 2022. PMID: 34902334 Free article.
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma.
Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad IB, Calderaro J, Bioulac-Sage P, Letexier M, Degos F, Clément B, Balabaud C, Chevet E, Laurent A, Couchy G, Letouzé E, Calvo F, Zucman-Rossi J. Guichard C, et al. Among authors: letouze e. Nat Genet. 2012 May 6;44(6):694-8. doi: 10.1038/ng.2256. Nat Genet. 2012. PMID: 22561517 Free PMC article.
Recurrent inactivating mutations of ARID2 in non-small cell lung carcinoma.
Manceau G, Letouzé E, Guichard C, Didelot A, Cazes A, Corté H, Fabre E, Pallier K, Imbeaud S, Le Pimpec-Barthes F, Zucman-Rossi J, Laurent-Puig P, Blons H. Manceau G, et al. Among authors: letouze e. Int J Cancer. 2013 May 1;132(9):2217-21. doi: 10.1002/ijc.27900. Epub 2012 Nov 20. Int J Cancer. 2013. PMID: 23047306 Free article.
Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation.
Pilati C, Letouzé E, Nault JC, Imbeaud S, Boulai A, Calderaro J, Poussin K, Franconi A, Couchy G, Morcrette G, Mallet M, Taouji S, Balabaud C, Terris B, Canal F, Paradis V, Scoazec JY, de Muret A, Guettier C, Bioulac-Sage P, Chevet E, Calvo F, Zucman-Rossi J. Pilati C, et al. Among authors: letouze e. Cancer Cell. 2014 Apr 14;25(4):428-41. doi: 10.1016/j.ccr.2014.03.005. Cancer Cell. 2014. PMID: 24735922 Free article.
DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma.
Villanueva A, Portela A, Sayols S, Battiston C, Hoshida Y, Méndez-González J, Imbeaud S, Letouzé E, Hernandez-Gea V, Cornella H, Pinyol R, Solé M, Fuster J, Zucman-Rossi J, Mazzaferro V, Esteller M, Llovet JM; HEPTROMIC Consortium. Villanueva A, et al. Among authors: letouze e. Hepatology. 2015 Jun;61(6):1945-56. doi: 10.1002/hep.27732. Epub 2015 Mar 18. Hepatology. 2015. PMID: 25645722 Free article.
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.
Schulze K, Imbeaud S, Letouzé E, Alexandrov LB, Calderaro J, Rebouissou S, Couchy G, Meiller C, Shinde J, Soysouvanh F, Calatayud AL, Pinyol R, Pelletier L, Balabaud C, Laurent A, Blanc JF, Mazzaferro V, Calvo F, Villanueva A, Nault JC, Bioulac-Sage P, Stratton MR, Llovet JM, Zucman-Rossi J. Schulze K, et al. Among authors: letouze e. Nat Genet. 2015 May;47(5):505-511. doi: 10.1038/ng.3252. Epub 2015 Mar 30. Nat Genet. 2015. PMID: 25822088 Free PMC article.
Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas.
Nault JC, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J. Nault JC, et al. Among authors: letouze e. Nat Genet. 2015 Oct;47(10):1187-93. doi: 10.1038/ng.3389. Epub 2015 Aug 24. Nat Genet. 2015. PMID: 26301494
AAV2 and Hepatocellular Carcinoma.
Nault JC, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J. Nault JC, et al. Among authors: letouze e. Hum Gene Ther. 2016 Mar;27(3):211-3. doi: 10.1089/hum.2016.002. Hum Gene Ther. 2016. PMID: 26935016 No abstract available.
Wild-type AAV Insertions in Hepatocellular Carcinoma Do Not Inform Debate Over Genotoxicity Risk of Vectorized AAV.
Nault JC, Mami I, La Bella T, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J. Nault JC, et al. Among authors: letouze e. Mol Ther. 2016 Apr;24(4):660-1. doi: 10.1038/mt.2016.47. Mol Ther. 2016. PMID: 27081717 Free PMC article. No abstract available.
93 results