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The Lyme disease spirochete's BpuR DNA/RNA-binding protein is differentially expressed during the mammal-tick infectious cycle, which affects translation of the SodA superoxide dismutase.
Mol Microbiol. 2019 Sep;112(3):973-991. doi: 10.1111/mmi.14336. Epub 2019 Jul 7.
Mol Microbiol. 2019.
PMID: 31240776
Free PMC article.
Transcriptomic insights on the virulence-controlling CsrA, BadR, RpoN, and RpoS regulatory networks in the Lyme disease spirochete.
Arnold WK, Savage CR, Lethbridge KG, Smith TC 2nd, Brissette CA, Seshu J, Stevenson B.
Arnold WK, et al. Among authors: lethbridge kg.
PLoS One. 2018 Aug 30;13(8):e0203286. doi: 10.1371/journal.pone.0203286. eCollection 2018.
PLoS One. 2018.
PMID: 30161198
Free PMC article.
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Borrelia burgdorferi, the Lyme disease spirochete, possesses genetically-encoded responses to doxycycline, but not to amoxicillin.
Saylor TC, Casselli T, Lethbridge KG, Moore JP, Owens KM, Brissette CA, Zückert WR, Stevenson B.
Saylor TC, et al. Among authors: lethbridge kg.
PLoS One. 2022 Sep 30;17(9):e0274125. doi: 10.1371/journal.pone.0274125. eCollection 2022.
PLoS One. 2022.
PMID: 36178885
Free PMC article.
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Mechanisms of proton relay and product release by Class A β-lactamase at ultrahigh resolution.
Lewandowski EM, Lethbridge KG, Sanishvili R, Skiba J, Kowalski K, Chen Y.
Lewandowski EM, et al. Among authors: lethbridge kg.
FEBS J. 2018 Jan;285(1):87-100. doi: 10.1111/febs.14315. Epub 2017 Nov 20.
FEBS J. 2018.
PMID: 29095570
Free PMC article.
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