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Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy.
Hingorani DV, Allevato MM, Camargo MF, Lesperance J, Quraishi MA, Aguilera J, Franiak-Pietryga I, Scanderbeg DJ, Wang Z, Molinolo AA, Alvarado D, Sharabi AB, Bui JD, Cohen EEW, Adams SR, Gutkind JS, Advani SJ. Hingorani DV, et al. Among authors: lesperance j. Nat Commun. 2022 Jul 5;13(1):3869. doi: 10.1038/s41467-022-31601-z. Nat Commun. 2022. PMID: 35790753 Free PMC article.
Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers.
Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA. Seguin L, et al. Among authors: lesperance j. Cancer Discov. 2017 Dec;7(12):1464-1479. doi: 10.1158/2159-8290.CD-17-0539. Epub 2017 Sep 11. Cancer Discov. 2017. PMID: 28893801 Free PMC article.
An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. Seguin L, et al. Among authors: lesperance j. Nat Cell Biol. 2014 May;16(5):457-68. doi: 10.1038/ncb2953. Epub 2014 Apr 20. Nat Cell Biol. 2014. PMID: 24747441 Free PMC article.
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia.
Shields DJ, Niessen S, Murphy EA, Mielgo A, Desgrosellier JS, Lau SK, Barnes LA, Lesperance J, Bouvet M, Tarin D, Cravatt BF, Cheresh DA. Shields DJ, et al. Among authors: lesperance j. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2189-94. doi: 10.1073/pnas.0911646107. Epub 2009 Dec 28. Proc Natl Acad Sci U S A. 2010. PMID: 20080647 Free PMC article.
277 results