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Chemogenetics revealed: DREADD occupancy and activation via converted clozapine.
Gomez JL, Bonaventura J, Lesniak W, Mathews WB, Sysa-Shah P, Rodriguez LA, Ellis RJ, Richie CT, Harvey BK, Dannals RF, Pomper MG, Bonci A, Michaelides M. Gomez JL, et al. Among authors: lesniak w. Science. 2017 Aug 4;357(6350):503-507. doi: 10.1126/science.aan2475. Science. 2017. PMID: 28774929 Free PMC article.
Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [11C]DPA-713 PET.
Coughlin JM, Yang T, Rebman AW, Bechtold KT, Du Y, Mathews WB, Lesniak WG, Mihm EA, Frey SM, Marshall ES, Rosenthal HB, Reekie TA, Kassiou M, Dannals RF, Soloski MJ, Aucott JN, Pomper MG. Coughlin JM, et al. Among authors: lesniak wg. J Neuroinflammation. 2018 Dec 19;15(1):346. doi: 10.1186/s12974-018-1381-4. J Neuroinflammation. 2018. PMID: 30567544 Free PMC article.
PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R).
Horti AG, Naik R, Foss CA, Minn I, Misheneva V, Du Y, Wang Y, Mathews WB, Wu Y, Hall A, LaCourse C, Ahn HH, Nam H, Lesniak WG, Valentine H, Pletnikova O, Troncoso JC, Smith MD, Calabresi PA, Savonenko AV, Dannals RF, Pletnikov MV, Pomper MG. Horti AG, et al. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1686-1691. doi: 10.1073/pnas.1812155116. Epub 2019 Jan 11. Proc Natl Acad Sci U S A. 2019. PMID: 30635412 Free PMC article.
The distribution of the alpha7 nicotinic acetylcholine receptor in healthy aging: An in vivo positron emission tomography study with [18F]ASEM.
Coughlin JM, Du Y, Rosenthal HB, Slania S, Min Koo S, Park A, Solomon G, Vranesic M, Antonsdottir I, Speck CL, Rootes-Murdy K, Lerner A, Rowe SP, Wang Y, Lesniak WG, Minn I, Bakker A, Smith GS, Dannals RF, Kuwabara H, Horti A, Wong DF, Pomper MG. Coughlin JM, et al. Neuroimage. 2018 Jan 15;165:118-124. doi: 10.1016/j.neuroimage.2017.10.009. Epub 2017 Oct 7. Neuroimage. 2018. PMID: 28993233 Free PMC article.
High Availability of the α7-Nicotinic Acetylcholine Receptor in Brains of Individuals with Mild Cognitive Impairment: A Pilot Study Using 18F-ASEM PET.
Coughlin JM, Rubin LH, Du Y, Rowe SP, Crawford JL, Rosenthal HB, Frey SM, Marshall ES, Shinehouse LK, Chen A, Speck CL, Wang Y, Lesniak WG, Minn I, Bakker A, Kamath V, Smith GS, Albert MS, Azad BB, Dannals RF, Horti A, Wong DF, Pomper MG. Coughlin JM, et al. J Nucl Med. 2020 Mar;61(3):423-426. doi: 10.2967/jnumed.119.230979. Epub 2019 Aug 16. J Nucl Med. 2020. PMID: 31420499 Free PMC article.
160 results