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Page 1
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AAB, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Cooper MA, Gambin Y, Francois M. Overman J, et al. Among authors: lesieur e. Elife. 2017 Jan 31;6:e21221. doi: 10.7554/eLife.21221. Elife. 2017. PMID: 28137359 Free PMC article.
Identification of novel markers of mouse fetal ovary development.
Chen H, Palmer JS, Thiagarajan RD, Dinger ME, Lesieur E, Chiu H, Schulz A, Spiller C, Grimmond SM, Little MH, Koopman P, Wilhelm D. Chen H, et al. Among authors: lesieur e. PLoS One. 2012;7(7):e41683. doi: 10.1371/journal.pone.0041683. Epub 2012 Jul 26. PLoS One. 2012. PMID: 22844512 Free PMC article.
Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development.
Kartopawiro J, Bower NI, Karnezis T, Kazenwadel J, Betterman KL, Lesieur E, Koltowska K, Astin J, Crosier P, Vermeren S, Achen MG, Stacker SA, Smith KA, Harvey NL, François M, Hogan BM. Kartopawiro J, et al. Among authors: lesieur e. Hum Mol Genet. 2014 Mar 1;23(5):1286-97. doi: 10.1093/hmg/ddt518. Epub 2013 Oct 24. Hum Mol Genet. 2014. PMID: 24163130
SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M. Chiang IK, et al. Among authors: lesieur e. Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15. Development. 2017. PMID: 28619820 Free PMC article.
Correction: SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development doi: 10.1242/dev.146241.
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Fossat N, Radziewic T, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Tam PPL, Carroll J, Dejana E, Schulte-Merker S, Hogan BM, Beltrame M, De Val S, Francois M. Chiang IK, et al. Among authors: lesieur e. Development. 2017 Oct 15;144(20):3847-3848. doi: 10.1242/dev.159715. Development. 2017. PMID: 29042478 Free PMC article. No abstract available.
A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development.
Pichol-Thievend C, Betterman KL, Liu X, Ma W, Skoczylas R, Lesieur E, Bos FL, Schulte D, Schulte-Merker S, Hogan BM, Oliver G, Harvey NL, Francois M. Pichol-Thievend C, et al. Among authors: lesieur e. Development. 2018 May 17;145(10):dev160184. doi: 10.1242/dev.160184. Development. 2018. PMID: 29773646 Free PMC article.
R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma.
Overman J, Fontaine F, Wylie-Sears J, Moustaqil M, Huang L, Meurer M, Chiang IK, Lesieur E, Patel J, Zuegg J, Pasquier E, Sierecki E, Gambin Y, Hamdan M, Khosrotehrani K, Andelfinger G, Bischoff J, Francois M. Overman J, et al. Among authors: lesieur e. Elife. 2019 Jul 30;8:e43026. doi: 10.7554/eLife.43026. Elife. 2019. PMID: 31358114 Free PMC article.
The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner.
Chiang IKN, Graus MS, Kirschnick N, Davidson T, Luu W, Harwood R, Jiang K, Li B, Wong YY, Moustaqil M, Lesieur E, Skoczylas R, Kouskoff V, Kazenwadel J, Arriola-Martinez L, Sierecki E, Gambin Y, Alitalo K, Kiefer F, Harvey NL, Francois M. Chiang IKN, et al. Among authors: lesieur e. EMBO J. 2023 Mar 1;42(5):e109032. doi: 10.15252/embj.2021109032. Epub 2023 Jan 30. EMBO J. 2023. PMID: 36715213 Free PMC article.
Use of dual section mRNA in situ hybridisation/immunohistochemistry to clarify gene expression patterns during the early stages of nephron development in the embryo and in the mature nephron of the adult mouse kidney.
Georgas K, Rumballe B, Wilkinson L, Chiu HS, Lesieur E, Gilbert T, Little MH. Georgas K, et al. Among authors: lesieur e. Histochem Cell Biol. 2008 Nov;130(5):927-42. doi: 10.1007/s00418-008-0454-3. Epub 2008 Jul 11. Histochem Cell Biol. 2008. PMID: 18618131
40 results