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Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells.
Stepanov AV, Xie J, Zhu Q, Shen Z, Su W, Kuai L, Soll R, Rader C, Shaver G, Douthit L, Zhang D, Kalinin R, Fu X, Zhao Y, Qin T, Baran PS, Gabibov AG, Bushnell D, Neri D, Kornberg RD, Lerner RA. Stepanov AV, et al. Among authors: lerner ra. Nat Biomed Eng. 2023 Oct 5. doi: 10.1038/s41551-023-01102-5. Online ahead of print. Nat Biomed Eng. 2023. PMID: 37798444
Switchable targeting of solid tumors by BsCAR T cells.
Stepanov AV, Kalinin RS, Shipunova VO, Zhang D, Xie J, Rubtsov YP, Ukrainskaya VM, Schulga A, Konovalova EV, Volkov DV, Yaroshevich IA, Moysenovich AM, Belogurov AA Jr, Zhang H, Telegin GB, Chernov AS, Maschan MA, Terekhov SS, Wu P, Deyev SM, Lerner RA, Gabibov AG, Altman S. Stepanov AV, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2210562119. doi: 10.1073/pnas.2210562119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343224 Free PMC article.
Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Qiang M, Ma P, Li Y, Liu H, Harding A, Min C, Wang F, Liu L, Yuan M, Ji Q, Tao P, Shi X, Li Z, Li T, Wang X, Zhang Y, Wu NC, Lee CD, Zhu X, Gilbert-Jaramillo J, Zhang C, Saxena A, Huang X, Wang H, James W, Dwek RA, Wilson IA, Yang G, Lerner RA. Qiang M, et al. Among authors: lerner ra. Adv Sci (Weinh). 2022 Jan;9(1):e2102181. doi: 10.1002/advs.202102181. Epub 2021 Oct 29. Adv Sci (Weinh). 2022. PMID: 34716683 Free PMC article.
Publisher Correction: Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications.
Favalli N, Bassi G, Pellegrino C, Millul J, De Luca R, Cazzamalli S, Yang S, Trenner A, Mozaffari NL, Myburgh R, Moroglu M, Conway SJ, Sartori AA, Manz MG, Lerner RA, Vogt PK, Scheuermann J, Neri D. Favalli N, et al. Among authors: lerner ra. Nat Chem. 2021 Jul;13(7):714. doi: 10.1038/s41557-021-00742-x. Nat Chem. 2021. PMID: 34103693 No abstract available.
Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications.
Favalli N, Bassi G, Pellegrino C, Millul J, De Luca R, Cazzamalli S, Yang S, Trenner A, Mozaffari NL, Myburgh R, Moroglu M, Conway SJ, Sartori AA, Manz MG, Lerner RA, Vogt PK, Scheuermann J, Neri D. Favalli N, et al. Among authors: lerner ra. Nat Chem. 2021 Jun;13(6):540-548. doi: 10.1038/s41557-021-00660-y. Epub 2021 Apr 8. Nat Chem. 2021. PMID: 33833446 Free PMC article.
376 results